(R)-N₁-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-N₂,N₂-dimethyloxalamide

Base Information

• Chemical Name: (R)-N₁-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-N₂,N₂-dimethyloxalamide
• CAS No.: 1223404-75-8
• Molecular Formula: C₂₀H₂₀F₂N₆O₂
• Molecular Weight: 414.415

Synonyms:(R)-N₁-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-N₂,N₂-dimethyloxalamide

Chemical Property of (R)-N₁-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-N₂,N₂-dimethyloxalamide

Chemical Property:

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Technology Process of (R)-N₁-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-N₂,N₂-dimethyloxalamide

There total 1 articles about (R)-N₁-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-N₂,N₂-dimethyloxalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-methyl 2-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-ylamino)-2-oxoacetate (1223404-82-7) + dimethyl amine (124-40-3) → (R)-N1-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-N2,N2-dimethyloxalamide (1223404-75-8)

Guidance literature:

In tetrahydrofuran; dichloromethane; at 20 ℃; Reflux;

upstream raw materials:

(R)-methyl 2-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-ylamino)-2-oxoacetate

dimethyl amine

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