N-Butyl-phthalamic acid ethyl ester

Base Information

• Chemical Name: N-Butyl-phthalamic acid ethyl ester
• CAS No.: 97166-64-8
• Molecular Formula: C₁₄H₁₉NO₃
• Molecular Weight: 249.31
• Mol file: 97166-64-8.mol

Synonyms:N-Butyl-phthalamic acid ethyl ester

Chemical Property of N-Butyl-phthalamic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-Butyl-phthalamic acid ethyl ester

There total 3 articles about N-Butyl-phthalamic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethanol (64-17-5) + N-butylisophthalimide (80991-83-9) → N-Butyl-phthalamic acid ethyl ester (97166-64-8)

Guidance literature:

at 25 ℃; for 3h;

Reference yield:

Phthaloyl dichloride (88-95-9) → N-Butyl-phthalamic acid ethyl ester (97166-64-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / triethylamine / benzene / 0.05 h / 20 °C

2: 85 percent / 3 h / 25 °C

With triethylamine; In benzene;

Reference yield:

monoethyl phthalate (2306-33-4) + N-butylamine (109-73-9,85404-21-3) → N-Butyl-phthalamic acid ethyl ester (97166-64-8)

Guidance literature:

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; Multistep reaction; 1.) THF, r.t., 40 min, 2.) r.t.;

DOI:10.1055/s-1998-2038

upstream raw materials:

ethanol

N-butylisophthalimide

monoethyl phthalate

N-butylamine

Downstream raw materials:

N-butylphthalimide