2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride

Base Information

Chemical Name:2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride
CAS No.:100947-97-5
Molecular Formula:C₁₁H₁₂F₃NO₂*ClH
Molecular Weight:283.678
Hs Code.:

Synonyms:2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride

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Chemical Property of 2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride

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Technology Process of 2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride

There total 2 articles about 2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 64-17-5
ethanol

: 82129-08-6
2-(3-Trifluoromethylphenyl)-2-trimethylsiloxyethanenitrile

: 100947-97-5
2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; at 5 ℃; for 16h;
DOI:10.1021/jm00155a030

Reference yield:

: 454-89-7
3-Trifluoromethylbenzaldehyde

: 100947-97-5
2-Hydroxy-2-(3-trifluoromethyl-phenyl)-acetimidic acid ethyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: ZnI₂ / CH₂Cl₂ / 65 h / Ambient temperature

2: 70 percent / HCl / 16 h / 5 °C

With hydrogenchloride; zinc(II) iodide; In dichloromethane;
DOI:10.1021/jm00155a030