(S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

Base Information

Chemical Name:(S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt
CAS No.:1016651-04-9
Molecular Formula:CH₄O₃S*C₂₄H₃₄F₂N₄O₆
Molecular Weight:608.661
Hs Code.:

(S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

Synonyms:(S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

Suppliers and Price of (S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

There total 2 articles about (S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 75-75-2,98527-29-8
methanesulfonic acid

: 1016651-10-7
(S)-N-{3-[3,5-difluoro-4-(4-((S)-2-carbobenzyloxyamino-3,3-dimethylpropionyl)-4-methoxymethyl-piperidine-1-yl)phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

: 1016651-04-9
(S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 10h; under 1551.49 Torr;

Reference yield:

: 957796-51-9
(5S)-N-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 1016651-04-9
(S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt

Guidance literature:: Multi-step reaction with 2 steps

1.1: dicyclohexyl-carbodiimide / dichloromethane / 0.5 h / 0 - 5 °C / Inert atmosphere

1.2: 48 h / 20 °C / Inert atmosphere

2.1: hydrogen / palladium 10% on activated carbon / methanol / 10 h / 20 °C / 1551.49 Torr

With hydrogen; dicyclohexyl-carbodiimide; palladium 10% on activated carbon; In methanol; dichloromethane;