(E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride

Base Information

Chemical Name:(E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride
CAS No.:1204230-72-7
Molecular Formula:C₂₃H₂₄N₂O₃*ClH
Molecular Weight:412.916
Hs Code.:

Synonyms:(E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride

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Chemical Property of (E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride

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Technology Process of (E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride

There total 2 articles about (E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 56915-77-6
1-[2-(4-methylpiperazin-1-yl)phenyl]ethanone

: 66885-68-5
(E)-p-formylcinnamic acid

: 1204230-72-7
(E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride

Guidance literature:: 1-[2-(4-methylpiperazin-1-yl)phenyl]ethanone; (E)-p-formylcinnamic acid; With potassium hydroxide; ethanol; In water; at 20 ℃; for 24h;

With hydrogenchloride; In ethanol; water;

Reference yield:

: 952390-98-6
C₂₃H₂₄N₂O₃

: 1204230-72-7
(E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; water;
DOI:10.1021/jm901502p

Reference yield:

: 6723-30-4
O-2-tetrahydro-2H-pyranhydroxylamine

: 1204230-72-7
(E)-3-(4-{(E)-3-[2-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylic acid hydrochloride

: C₂₈H₃₃N₃O₄

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 24h;