1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate

Base Information

• Chemical Name: 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate
• CAS No.: 98649-15-1
• Molecular Formula: C₁₄H₁₆N₂O₅
• Molecular Weight: 292.291
• Mol file: 98649-15-1.mol

Synonyms:1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate

Chemical Property of 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate

There total 6 articles about 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 1-benzyloxycarbonyl-2-oxo-4-imidazolidinecarboxylate (76453-28-6) + methyl iodide (74-88-4) → 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate (98649-15-1)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 15h; Ambient temperature;

Reference yield: 4.0%

methyl 3-benzyloxycarbonyl-2-oxo-4-imidazolidinecarboxylate (76453-27-5) + methyl iodide (74-88-4) → 1-methyl-2-oxo-3-benzyloxy-carbonyl-4-carbomethoxy-imidazolidine (98296-71-0) + 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate (98649-15-1)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 15h; Ambient temperature;

Reference yield:

methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate (168399-08-4) + methyl iodide (74-88-4) → 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate (98649-15-1)

Guidance literature:

methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

methyl iodide; In N,N-dimethyl-formamide; at 22 ℃; for 18h;

upstream raw materials:

methyl 3-benzyloxycarbonyl-2-oxo-4-imidazolidinecarboxylate

methyl iodide

methyl 1-benzyloxycarbonyl-2-oxo-4-imidazolidinecarboxylate

2-oxo-imidazolidine-1,5-dicarboxylic acid 1-benzyl ester

Downstream raw materials:

N-[(2,4-dichlorophenyl)methyl]-3-methyl-1-(1-methylethyl)-2-oxo-4-imidazolidinecarboxamide

N-[(2-chloro-3,4-difluorophenyl)methyl]-3-methyl-2-oxo-4-imidazolidinecarboxamide

N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-4-imidazolidinecarboxamide

1-cyclopentyl-N-[(2,4-dichlorophenyl)methyl]-3-methyl-2-oxo-4-imidazolidinecarboxamide