168399-08-4

Basic information

• Product Name: methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate
• Synonyms: methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate
• CAS NO: 168399-08-4
• Molecular Weight: 278.265
• Mol File: 168399-08-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate(168399-08-4)
• EPA Substance Registry System: methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate(168399-08-4)

Safety Data

• Hazardous Substances Data: 168399-08-4(Hazardous Substances Data)

Upstream product

• 4668-37-5 N-(benzyloxycarbonyl)asparagine methyl ester 
• 67-56-1 methanol 
• 59760-01-9 (S)-2-oxo-imidazolidine-1,5-dicarboxylic acid 1-benzyl ester 

Downstream Products

• 169393-28-6 methyl 1-phenylacetyl-3-benzyloxycarbonylimidazolidin-2-one-4(S)-carboxylate 
• 90242-55-0 Methyl (4S)-3-<(benzyloxy)carbonyl>-1-methyl-2-oxoimidazolidine-4-carboxylate 
• 459454-25-2 methyl 3-benzyloxycarbonyl-1-bromoacetyl-2-oxoimidazolidine-4(S)-carboxylate 
• 90157-23-6 benzyl (S)-5-(hydroxymethyl)-3-methyl-2-oxoimidazolidine-1-carboxylate 
• 98649-15-1 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate 
• 168399-09-5 Methyl (4S)-1-Methyl-2-oxoimidazolidine-4-carboxylate 
• 459454-27-4 methyl 3-benzyloxycarbonyl-1-[(1-benzyl-5-oxopyrrolidine-2(S)-carbonyloxy)acetyl]-2-oxoimidazolidine-4(S)-carboxylate 
• 459454-30-9 methyl 1-[(1-benzyl-5-oxopyrrolidine-2(S)-carbonyloxy)acetyl]-2-oxoimidazolidine-4(S)-carboxylate 
• 437606-07-0 methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate 
• 459454-28-5 methyl 1-(l-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate 
• 860016-07-5 methyl 1-[1-benzenesulfonyl-pyrrolidine-2'(S)-carbonyl]-3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate 
• 860016-08-6 methyl 1-[1-benzenesulfonyl-pyrrolidine-2'(R)-carbonyl]-3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate 

Relevant articles and documents

Bicyclic-Fused Heteroaryl or Aryl Compounds

Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

IMIDAZOLIDINE CARBOXAMIDE DERIVATIVES AS P2X7 MODULATORS

The present invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof: The compounds or salts modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor (P2X7 receptor antagonists). The invention also provides the use of such compounds or salts, or pharmaceutical compositions thereof, in the treatment or prevention of disorders / diseases mediated by the P2X7 receptor, for example pain, inflammation or a neurodegenerative disease, in particular pain such as inflammatory pain, neuropathic pain or visceral pain.

First attempts at differential diastereoselection in catalytic reactions of N-chirally substituted dirhodium(II) tetrakis[methyl 2-oxoimidazolidine-4(S)-carboxylates] with diazoacetates

Chiral attachments on 2-oxoimidazolidine-4(S)-carboxylate ligands for dirhodium(II) can provide differential diastereoselection in catalytic reactions of diazo compounds. The synthesis of these heterocyclic ligands from the readily available amino acid as