5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)-2',3'-bis-O-pivaloyladenosine

Base Information

• Chemical Name: 5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)-2',3'-bis-O-pivaloyladenosine
• CAS No.: 1401415-45-9
• Molecular Formula: C₂₉H₃₈N₈O₇
• Molecular Weight: 610.67

Synonyms:5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)-2',3'-bis-O-pivaloyladenosine

Chemical Property of 5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)-2',3'-bis-O-pivaloyladenosine

Chemical Property:

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Technology Process of 5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)-2',3'-bis-O-pivaloyladenosine

There total 1 articles about 5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)-2',3'-bis-O-pivaloyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N6-(N-phenylcarbamoyl)adenosine (1092548-23-6) + pivaloyl chloride (3282-30-2) → 5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N6-(N-phenylcarbamoyl)-2',3'-bis-O-pivaloyladenosine (1401415-45-9)

Guidance literature:

With pyridine; at 70 ℃;

DOI:10.1016/j.bmcl.2012.08.050

upstream raw materials:

5'-deoxy-5'-[(N-methylcarbamoyl)amino]-N₆-(N-phenylcarbamoyl)adenosine

pivaloyl chloride

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