Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

Base Information

Chemical Name:Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone
CAS No.:81816-78-6
Molecular Formula:C₂₀H₂₂N₂O₂
Molecular Weight:322.407
Hs Code.:

Synonyms:Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

Suppliers and Price of Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

There total 3 articles about Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 92-54-6
4-phenyl-1-piperazine

: 77039-78-2
2,3-dihydro-4H-benzopyran-2-carboxylic acid chloride

: 81816-78-6
Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

Guidance literature:: With triethylamine; In benzene; for 24h;

Reference yield:

: 4940-39-0
acide chromone carboxylique-2

: 81816-78-6
Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / hydrogene / Pd/C / acetic acid / 70 °C

2: thionyl chloride / CHCl₃ / 3 h / Heating

3: 90 percent / triethylamine / benzene / 24 h

With thionyl chloride; hydrogen; triethylamine; palladium on activated charcoal; In chloroform; acetic acid; benzene;

Reference yield:

: 51939-71-0
chroman-2-carboxylic acid

: 81816-78-6
Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / CHCl₃ / 3 h / Heating

2: 90 percent / triethylamine / benzene / 24 h

With thionyl chloride; triethylamine; In chloroform; benzene;