4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride

Base Information

Chemical Name:4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride
CAS No.:1609575-54-3
Molecular Formula:C₂₃H₂₀F₇N₃O₂*ClH
Molecular Weight:539.88
Hs Code.:

Synonyms:4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride

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Chemical Property of 4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride

Chemical Property:

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Technology Process of 4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride

There total 7 articles about 4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1609575-70-3
4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine

: 1609575-54-3
4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; diethyl ether; hexane;

Reference yield:

: 1609575-64-5
4,4,4-trifluoro-3-[2-(3-trifluoromethylphenyl)-morpholin-4-ylmethyl]-butyronitrile

: 1609575-54-3
4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / 4 h / 110 °C

2: trichlorophosphate / 4 h / 110 °C

3: hydrogenchloride / diethyl ether; hexane; 1,4-dioxane

With hydrogenchloride; trichlorophosphate; In 1,4-dioxane; diethyl ether; hexane; water;

Reference yield:

: 1609575-65-6
4,4,4-trifluoro-3-[2-(3-trifluoromethyl-phenyl)-morpholin-4-ylmethyl]-butyric acid hydrochloride

: 1609575-54-3
4-{3,3,3-trifluoro-2-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl}-2-(3-trifluoromethyl-phenyl)-morpholine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / 4 h / 110 °C

2: hydrogenchloride / diethyl ether; hexane; 1,4-dioxane

With hydrogenchloride; trichlorophosphate; In 1,4-dioxane; diethyl ether; hexane;