Technology Process of ethyl (2E)-5-(1-triphenylmethyl-1H-imidazol-4-yl)pent-2-enoate
There total 7 articles about ethyl (2E)-5-(1-triphenylmethyl-1H-imidazol-4-yl)pent-2-enoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 75 percent / triethylamine / tetrahydrofuran / 16 h / 20 °C
2: 99 percent / H2 / Pd/C / methanol / 4 h
3: 70 percent / LiAlH4 / tetrahydrofuran / 6 h / Heating
4: 78 percent / oxalyl chloride; DMSO; triethylamine / CH2Cl2 / 2 h / -60 - 20 °C
5: 75 percent / NaH / tetrahydrofuran / 6 h / 20 °C
With
lithium aluminium tetrahydride; oxalyl dichloride; hydrogen; sodium hydride; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane;
4: Swern oxidation / 5: Wittig reaction;
DOI:10.1016/j.bmc.2005.09.002
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 75 percent / triethylamine / tetrahydrofuran / 16 h / 20 °C
2: 99 percent / H2 / Pd/C / methanol / 4 h
3: 70 percent / LiAlH4 / tetrahydrofuran / 6 h / Heating
4: 78 percent / oxalyl chloride; DMSO; triethylamine / CH2Cl2 / 2 h / -60 - 20 °C
5: 75 percent / NaH / tetrahydrofuran / 6 h / 20 °C
With
lithium aluminium tetrahydride; oxalyl dichloride; hydrogen; sodium hydride; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane;
4: Swern oxidation / 5: Wittig reaction;
DOI:10.1016/j.bmc.2005.09.002
