methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

Base Information

• Chemical Name: methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate
• CAS No.: 1330527-03-1
• Molecular Formula: C₂₂H₁₇NO₄
• Molecular Weight: 359.381
• Mol file: 1330527-03-1.mol

Synonyms:methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

Chemical Property of methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

There total 2 articles about methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-hydroxynaphtho-1,4-quinone (83-72-7) + benzaldehyde (100-52-7) + methyl (E)-3-aminocrotonate (14205-39-1) → methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate (1330527-03-1)

Guidance literature:

With sulfonated carbonaceous material from polyvinyl alcohol and hydroxyethylsulfuric acid; In water; at 80 ℃; for 6h; Reagent/catalyst; Solvent; Temperature; regioselective reaction; Catalytic behavior; Sealed tube;

DOI:10.1002/jhet.2799

Reference yield: 83.0%

2-hydroxynaphtho-1,4-quinone (83-72-7) + benzaldehyde (100-52-7) + acetoacetic acid methyl ester (105-45-3) → methyl 2-methyl-5,10-dioxo-4-phenyl-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate (1330527-03-1)

Guidance literature:

With ammonium acetate; In ethanol; at 100 ℃; for 0.166667h; regioselective reaction; Microwave irradiation; Sealed vial;

DOI:10.1016/j.tetlet.2011.06.102

upstream raw materials:

2-hydroxynaphtho-1,4-quinone

benzaldehyde

acetoacetic acid methyl ester

methyl (E)-3-aminocrotonate