[(1R,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl] 2-chloroacetate

Base Information

Chemical Name:[(1R,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl] 2-chloroacetate
CAS No.:71804-27-8
Molecular Formula:C18H25 Cl O2
Molecular Weight:308.848
Hs Code.:
European Community (EC) Number:622-085-9
Mol file:71804-27-8.mol

Synonyms:(1R,2S,5R)-(+)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexyl chloroacetate;71804-27-8

Suppliers and Price of [(1R,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl] 2-chloroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(1R,2S,5R)-(+)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexyl chloroacetate 99%
1g
$ 119.00

Chem-Impex
(1R,2S,5R)-(+)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexylchloroacetate,98.5-101.5%(Assaybytitration) 98.5-101.5%(Assaybytitration)
1G
$ 118.81

American Custom Chemicals Corporation
(1R,2S,5R)-(+)-5-METHYL-2-(1-METHYL-1-PHENYLETHYL)CYCLOHEXYL CHLOROACETATE 95.00%
1G
$ 719.65

Total 5 raw suppliers

Chemical Property of [(1R,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl] 2-chloroacetate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:82-84 °C(lit.)
Refractive Index:1.522
Boiling Point:385.281°C at 760 mmHg
Flash Point:188.265°C
PSA：26.30000
Density:1.084g/cm³
LogP:4.55100
XLogP3:5.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:308.1543077
Heavy Atom Count:21
Complexity:347

Purity/Quality:

98%,99%, ^*data from raw suppliers

(1R,2S,5R)-(+)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexyl chloroacetate 99% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC(C(C1)OC(=O)CCl)C(C)(C)C2=CC=CC=C2
Isomeric SMILES:C[C@@H]1CCC([C@@H](C1)OC(=O)CCl)C(C)(C)C2=CC=CC=C2
Uses (1R,2S,5R)-(+)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexyl chloroacetate may be used in the synthesis of (-)-8-phenyl-menthol, (+)-8-phenylmenthyl isocyanoacetate and (+)-cularine.

Technology Process of [(1R,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl] 2-chloroacetate

There total 8 articles about [(1R,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl] 2-chloroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 8-phenylmenthol

: 79-04-9
chloroacetyl chloride

: 71804-27-8
(1R,2S,5R)-(+)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl chloroacetate

Guidance literature:: In diethyl ether; N,N-dimethyl-aniline; at -5 - 45 ℃; for 13h; Schlenk technique; Inert atmosphere;
DOI:10.1021/jacs.5b01517

Reference yield: 71.0%

: 152481-90-8
(1R,2S,5R)-(+)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl dichloroacetate

: 71804-27-8
(1R,2S,5R)-(+)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl chloroacetate

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; In tetrahydrofuran; at 0 ℃; for 0.5h;
DOI:10.1021/jo9803838