Technology Process of C26H30ClF3N2O4
There total 16 articles about C26H30ClF3N2O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
thionyl chloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: N-iodo-succinimide; potassium carbonate / N,N-dimethyl-formamide / 3 h / 60 °C
2.1: P,P-dichlorophenylphosphine oxide / 136 °C
2.2: 0 - 20 °C / pH 6
3.1: potassium carbonate / dimethyl sulfoxide / 2 h / 100 °C
4.1: bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 4.08 - 6.08 h / Heating / reflux
5.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; acetone; tert-butyl alcohol / 20 °C
6.1: sodium periodate / tetrahydrofuran; water / 6.08 h / 0 - 20 °C
7.1: sodium tetrahydroborate / methanol / 2 h / 20 °C
8.1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 0.5 h / 20 °C
With
P,P-dichlorophenylphosphine oxide; sodium tetrahydroborate; sodium periodate; N-iodo-succinimide; osmium(VIII) oxide; thionyl chloride; potassium carbonate; 4-methylmorpholine N-oxide; N,N-dimethyl-formamide;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: P,P-dichlorophenylphosphine oxide / 136 °C
1.2: 0 - 20 °C / pH 6
2.1: potassium carbonate / dimethyl sulfoxide / 2 h / 100 °C
3.1: bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 4.08 - 6.08 h / Heating / reflux
4.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; acetone; tert-butyl alcohol / 20 °C
5.1: sodium periodate / tetrahydrofuran; water / 6.08 h / 0 - 20 °C
6.1: sodium tetrahydroborate / methanol / 2 h / 20 °C
7.1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 0.5 h / 20 °C
With
P,P-dichlorophenylphosphine oxide; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; thionyl chloride; potassium carbonate; 4-methylmorpholine N-oxide; N,N-dimethyl-formamide;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; acetone; tert-butyl alcohol;