Technology Process of C17H25NO4
There total 6 articles about C17H25NO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
tert-butyl (2R,3R)-4-hydroxy-3-methyl-1-phenylbutan-2-ylcarbamate;
With
sodium periodate; rhodium(III) chloride hydrate;
In
tetrachloromethane; water; acetonitrile;
at 0 - 20 ℃;
for 5h;
Inert atmosphere;
methanol;
With
trimethylsilyl diazomethane;
In
diethyl ether; benzene;
at 20 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1021/ja5017206
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid / ethyl acetate / 30 h / 0 °C / Inert atmosphere
2.1: sodium tetrahydroborate / methanol / 1 h / 0 °C / Inert atmosphere
3.1: rhodium(III) chloride hydrate; sodium periodate / water; acetonitrile; tetrachloromethane / 5 h / 0 - 20 °C / Inert atmosphere
3.2: 0.5 h / 20 °C / Inert atmosphere
With
sodium tetrahydroborate; sodium periodate; (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; rhodium(III) chloride hydrate;
In
methanol; tetrachloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1021/ja5017206
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid / ethyl acetate / 0.02 h / 40 °C / Inert atmosphere
2.1: sodium tetrahydroborate / methanol / 1 h / 0 °C / Inert atmosphere
3.1: rhodium(III) chloride hydrate; sodium periodate / water; acetonitrile; tetrachloromethane / 5 h / 0 - 20 °C / Inert atmosphere
3.2: 0.5 h / 20 °C / Inert atmosphere
With
sodium tetrahydroborate; sodium periodate; (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; rhodium(III) chloride hydrate;
In
methanol; tetrachloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1021/ja5017206
