(S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

Base Information

Chemical Name:(S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester
CAS No.:174359-48-9
Molecular Formula:C₂₂H₂₆N₂O₆
Molecular Weight:414.458
Hs Code.:

Synonyms:(S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

Suppliers and Price of (S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

There total 5 articles about (S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 15761-38-3
L-N-Boc-Ala

: 7107-59-7
4-(N-Benzyloxycarbonylamino)phenol

: 174359-48-9
(S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 1h;
DOI:10.1248/cpb.43.2082

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 174359-48-9
(S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 74 percent / TsOH*H₂O / benzene / 0.5 h / 60 °C

2: H₂ / 10percent Pd/C / ethanol / 20 h / Ambient temperature

3: CHCl₃ / 2 h / Ambient temperature

4: 97 percent / TsOH*H₂O / methanol / 1 h / Heating

5: 66 percent / DMAP, DCC / CH₂Cl₂; dimethylformamide / 1 h / 0 °C

With dmap; hydrogen; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide; benzene;
DOI:10.1248/cpb.43.2082

Reference yield:

: 20443-91-8
2-(4-nitrophenoxy)tetrahydropyran

: 174359-48-9
(S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / ethanol / 20 h / Ambient temperature

2: CHCl₃ / 2 h / Ambient temperature

3: 97 percent / TsOH*H₂O / methanol / 1 h / Heating

4: 66 percent / DMAP, DCC / CH₂Cl₂; dimethylformamide / 1 h / 0 °C

With dmap; hydrogen; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide;
DOI:10.1248/cpb.43.2082