CYCLOBUTANECARBOXAMIDINE HYDROCHLORIDE

Base Information

• Chemical Name: CYCLOBUTANECARBOXAMIDINE HYDROCHLORIDE
• CAS No.: 71690-89-6
• Molecular Formula: C5H10 N2 . Cl H
• Molecular Weight: 134.609
• Hs Code.: 2925290090
• Mol file: 71690-89-6.mol

Synonyms:Cyclobutanecarboximidamide,monohydrochloride (9CI)

Chemical Property of CYCLOBUTANECARBOXAMIDINE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 2.64mmHg at 25°C
• Melting Point: ca 160℃
• Refractive Index: 1.609
• Boiling Point: 158.3°C at 760 mmHg
• Flash Point: 49.6°C
• PSA: 49.87000
• Density: 1.26g/cm³
• LogP: 2.32450
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic

Purity/Quality:

99% ^*data from raw suppliers

cyclobutanecarboximidamidehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CYCLOBUTANECARBOXAMIDINE HYDROCHLORIDE

There total 3 articles about CYCLOBUTANECARBOXAMIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclobutanecarbonitrile (4426-11-3) → cyclobutanecarboximidamide hydrochloride (71690-89-6)

Guidance literature:

Reference yield:

C6H11NO*ClH → cyclobutanecarboximidamide hydrochloride (71690-89-6)

Guidance literature:

With ammonium chloride; In methanol;

DOI:10.1016/j.bmcl.2011.03.038

Reference yield:

→ cyclobutanecarboximidamide hydrochloride (71690-89-6)

Guidance literature:

upstream raw materials:

cyclobutanecarbonitrile

Refernces

• 1、 Young, Robert J.,Alderton, Wendy,Angell, Anthony D.R.,Beswick, Paul J.,Brown, David,Chambers, C. Lynn,Crowe, Miriam C.,Dawson, John,Hamlett, Christopher C.F.,Hodgson, Simon T.,Kleanthous, Savvas,Knowles, Richard G.,Russell, Linda J.,Stocker, Richard,Woolven, James M.. "Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; The identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor". . p. 3037 - 3040. Retrieved 2011/06/26.
• 2、 -. "11B-HSD1 inhibitors for the treatment of diabetes". Page/Page column 12. . Retrieved 2008/06/13.