3,5-dimethoxybenzyl thiocyanate

Base Information

• Chemical Name: 3,5-dimethoxybenzyl thiocyanate
• CAS No.: 1274916-84-5
• Molecular Formula: C₁₀H₁₁NO₂S
• Molecular Weight: 209.269
• Mol file: 1274916-84-5.mol

Synonyms:3,5-dimethoxybenzyl thiocyanate

Chemical Property of 3,5-dimethoxybenzyl thiocyanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-dimethoxybenzyl thiocyanate

There total 1 articles about 3,5-dimethoxybenzyl thiocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3,5-dimethoxybenzyl bromide (877-88-3) + potassium thioacyanate (333-20-0) → 3,5-dimethoxybenzyl thiocyanate (1274916-84-5)

Guidance literature:

In acetonitrile; at 20 ℃;

DOI:10.1016/j.tet.2010.11.104

Reference yield: 89.0%

1-bromo-1-propene (590-14-7) + 3,5-dimethoxybenzyl thiocyanate (1274916-84-5) → 3,5-dimethoxybenzyl 1-propynyl sulfide (1274916-43-6)

Guidance literature:

1-bromo-1-propene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Inert atmosphere;

3,5-dimethoxybenzyl thiocyanate; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.11.104

upstream raw materials:

3,5-dimethoxybenzyl bromide

potassium thioacyanate

Downstream raw materials:

3,5-dimethoxybenzyl 1-propynyl sulfide