3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Base Information

Chemical Name:3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid
CAS No.:1455089-90-3
Molecular Formula:C₂₂H₁₉N₃O₄
Molecular Weight:389.411
Hs Code.:

Synonyms:3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Suppliers and Price of 3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

There total 8 articles about 3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1392841-25-6
3-amino-2,2-dimethylpropionic acid TFA salt

: 1455094-19-5
1-cyano-4-hydroxy-7-phenylisoquinoline-3-carboxylic acid methyl ester

: 1455089-90-3
3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Guidance literature:: With sodium methylate; In ethanol; at 150 ℃; for 2h; Microwave irradiation;

Reference yield:

: 1572-98-1
2-cyano-2-methyl-propionic acid ethyl ester

: 1455089-90-3
3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen / ethanol / 20 h / 20 °C

2: sodium hydroxide / methanol; water / 6 h / 20 °C

3: dichloromethane / 3 h / 20 °C

4: sodium methylate / ethanol / 2 h / 150 °C / Microwave irradiation

With hydrogen; sodium methylate; sodium hydroxide; In methanol; ethanol; dichloromethane; water;

Reference yield:

: 59193-77-0
3-amino-2,2-dimethylpropionic acid ethyl ester

: 1455089-90-3
3-[(1-cyano-4-hydroxy-7-phenylisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / methanol; water / 6 h / 20 °C

2: dichloromethane / 3 h / 20 °C

3: sodium methylate / ethanol / 2 h / 150 °C / Microwave irradiation

With sodium methylate; sodium hydroxide; In methanol; ethanol; dichloromethane; water;