trans-4-(Maleimidomethyl)cyclohexanecarboxylic acid

Base Information

Chemical Name:trans-4-(Maleimidomethyl)cyclohexanecarboxylic acid
CAS No.:64987-82-2
Molecular Formula:C₁₂H₁₅NO₄
Molecular Weight:237.255
Hs Code.:2925190090
European Community (EC) Number:835-612-4,835-889-1
UNII:7CN76JAX09
DSSTox Substance ID:DTXSID801145980
Nikkaji Number:J2.951.386D
Wikidata:Q27268077
Mol file:64987-82-2.mol

Synonyms:69907-67-1;64987-82-2;TRANS-4-(MALEIMIDOMETHYL)CYCLOHEXANECARBOXYLIC ACID;trans-4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid;N-[4-(-Carboxycyclohexylmethyl)]maleimide;Mal-AMCHC-OH;4-(Maleimidomethyl)cyclohexanecarboxylic acid;N-(4-Carboxycyclohexylmethyl)maleimide;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid;4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid;4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylic Acid;7CN76JAX09;MFCD03093740;MFCD11519178;Cyclohexanecarboxylic acid, 4-((2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl)-;Cyclohexanecarboxylic acid, 4-((2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl)-, trans-;4-(n-maleimidomethyl)cyclohexane-1-carboxylic acid;trans-4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid;4-(Maleimidomethyl)cyclohexanecarboxylicAcid;(1R,4R)-4-((2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)METHYL)CYCLOHEXANECARBOXYLIC ACID;Mal-AMCHC;UNII-7CN76JAX09;trans-4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexanecarboxylic acid;Trans-4-(Maleimidomethyl)cyclohexanecarboxylicAcid;4-(Maleimidomethyl)cyclohexanecarboxylic acid, E-;SCHEMBL159817;SCHEMBL890390;(Discontinued, see C177860);DTXSID801145980;AMY13237;AMY21605;FD6031;AKOS015995272;AKOS016014251;CS-W006952;DS-6035;4-[(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)METHYL]CYCLOHEXANECARBOXYLIC ACID;N-(4-carboxycyclohexylmethyl)-maleimide;AC-32531;BP-20232;BS-29029;HY-42359;SY069051;SY247856;TRIALLYL1,2,4-BENZENETRICARBOXYLATE;A8847;CS-0021355;FT-0604025;FT-0604080;M3218;M3219;A19079;C70531;EN300-6487298;EN300-7363655;J-513759;Q27268077;trans-4-(maleimidomethyl)cyclohexane-1-carboxylic acid;Z1793625431;4-(MALEIMIDOMETHYL)CYCLOHEXANECARBOXYLIC ACID, TRANS-;4-((2,5-DIOXO-2H-PYRROL-1(5H)-YL)METHYL)CYCLOHEXANECARBOXYLICACID;(1r,4r)-4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid;4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid

Suppliers and Price of trans-4-(Maleimidomethyl)cyclohexanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[4-(-Carboxycyclohexylmethyl)]maleimide
25mg
$ 110.00

TCI Chemical
4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
1G
$ 222.00

TCI Chemical
4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
5G
$ 780.00

SynQuest Laboratories
4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid
500 mg
$ 600.00

Crysdot
4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylicacid 95+%
1g
$ 523.00

Chemenu
4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carboxylicacid 95%
1g
$ 489.00

BroadPharm
4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylicacid 96%
500 MG
$ 260.00

Biosynth Carbosynth
N-[4-(-Carboxycyclohexylmethyl)]maleimide
2 g
$ 100.00

Biosynth Carbosynth
N-[4-(-Carboxycyclohexylmethyl)]maleimide
5 g
$ 150.00

Biosynth Carbosynth
N-[4-(-Carboxycyclohexylmethyl)]maleimide
1 g
$ 60.00

Total 19 raw suppliers

Chemical Property of trans-4-(Maleimidomethyl)cyclohexanecarboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:157-158°C
Refractive Index:1.568
Boiling Point:433.582°C at 760 mmHg
PKA:4.80±0.10(Predicted)
Flash Point:216.023°C
PSA：74.68000
Density:1.33g/cm³
LogP:0.74030
Storage Temp.:-20°C Freezer
Solubility.:Chloroform, Methanol
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:237.10010796
Heavy Atom Count:17
Complexity:362

Purity/Quality:

97% ^*data from raw suppliers

N-[4-(-Carboxycyclohexylmethyl)]maleimide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)O
Description 4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Uses A sulfhydryl crosslinking reagent An amino reactive reagent. A sulfhydryl crosslinking reagent.

Technology Process of trans-4-(Maleimidomethyl)cyclohexanecarboxylic acid

There total 9 articles about trans-4-(Maleimidomethyl)cyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%