(R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol

Base Information

Chemical Name:(R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol
CAS No.:1427301-52-7
Molecular Formula:C₁₂H₁₅N₃O₃
Molecular Weight:249.269
Hs Code.:

Synonyms:(R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol

Suppliers and Price of (R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of (R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol

There total 2 articles about (R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 169315-44-0
2-azido-1-(4-hydroxyphenyl)ethanone

: 1423-60-5
methyl ethynyl ketone

: 1427301-52-7
(R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol

Guidance literature:: 2-azido-1-(4-hydroxyphenyl)ethanone; methyl ethynyl ketone; In aq. phosphate buffer; dimethyl sulfoxide; isopropyl alcohol; at 30 ℃; for 24h; pH=7.5; Microbiological reaction; Enzymatic reaction;

With copper; copper(II) sulfate; In aq. phosphate buffer; water; dimethyl sulfoxide; isopropyl alcohol; at 60 - 80 ℃; for 24h; Reagent/catalyst; stereoselective reaction;
DOI:10.1039/c3cc38674k

Reference yield:

: 2491-38-5
2-bromo-1-(4'-hydroxyphenyl)-1-ethanone

: 1427301-52-7
(R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium azide / water; ethanol / 20 °C

2.1: alcohol dehydrogenase-A expressed in E_. coli / aq. phosphate buffer; isopropyl alcohol; dimethyl sulfoxide / 24 h / 30 °C / pH 7.5 / Microbiological reaction; Enzymatic reaction

2.2: 24 h / 60 - 80 °C

With sodium azide; In aq. phosphate buffer; ethanol; water; dimethyl sulfoxide; isopropyl alcohol;
DOI:10.1039/c3cc38674k