2-Azido-1-(4-hydroxyphenyl)ethanone

Base Information

Chemical Name:2-Azido-1-(4-hydroxyphenyl)ethanone
CAS No.:169315-44-0
Molecular Formula:C8H7N3O2
Molecular Weight:177.162
Hs Code.:
DSSTox Substance ID:DTXSID90697180
Nikkaji Number:J3.196.561F
Wikidata:Q82626998
Mol file:169315-44-0.mol

Synonyms:2-AZIDO-1-(4-HYDROXYPHENYL)ETHANONE;169315-44-0;2-Azido-1-(4-hydroxyphenyl)ethan-1-one;DTXSID90697180;AKOS040790660;4-Hydroxy-alpha-azidomethylbenzaldehyde;F1901-3152

Suppliers and Price of 2-Azido-1-(4-hydroxyphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Azido-1-(4-hydroxyphenyl)ethanone

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:177.053826475
Heavy Atom Count:13
Complexity:228

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CN=[N+]=[N-])O

Technology Process of 2-Azido-1-(4-hydroxyphenyl)ethanone

There total 4 articles about 2-Azido-1-(4-hydroxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 2491-38-5
2-bromo-1-(4'-hydroxyphenyl)-1-ethanone

: 169315-44-0
2-azido-1-(4-hydroxyphenyl)ethanone

Guidance literature:: With sodium azide; In methanol; water; at 0 - 20 ℃;
DOI:10.1016/j.tetlet.2021.153482

Reference yield: 89.0%

: 2200-91-1
4-ethynylphenol

: 169315-44-0
2-azido-1-(4-hydroxyphenyl)ethanone

Guidance literature:: With dipotassium peroxodisulfate; trimethylsilylazide; oxygen; copper diacetate; In dimethyl sulfoxide; at 20 - 25 ℃; for 12h;

Reference yield:

: 99-93-4
4-Hydroxyacetophenone

: 169315-44-0
2-azido-1-(4-hydroxyphenyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: dioxane dibromide / 1,4-dioxane; diethyl ether / 12 h / 0 - 23 °C

2: sodium azide / acetone; water / 24 h

With sodium azide; dioxane dibromide; In 1,4-dioxane; diethyl ether; water; acetone;
DOI:10.1021/acs.orglett.8b00697