Ethanone, 1-[2-(2-propenyl)phenyl]- (9CI)

Base Information

• Chemical Name: Ethanone, 1-[2-(2-propenyl)phenyl]- (9CI)
• CAS No.: 64664-07-9
• Molecular Formula: C11H12 O
• Molecular Weight: 160.216
• Hs Code.: 2914399090
• Mol file: 64664-07-9.mol

Synonyms:Ethanone,1-[2-(2-propenyl)phenyl]- (9CI); 2-Allylacetophenone

Chemical Property of Ethanone, 1-[2-(2-propenyl)phenyl]- (9CI)

Chemical Property:

• Boiling Point: 250.1±19.0 °C(Predicted)
• PSA: 17.07000
• Density: 0.968±0.06 g/cm3(Predicted)
• LogP: 2.61770

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-[2-(2-propenyl)phenyl]- (9CI)

There total 11 articles about Ethanone, 1-[2-(2-propenyl)phenyl]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

allyl bromide (106-95-6) + 1-bromo-2-(1,1-dimethoxyethyl)benzene (120254-80-0) → 1-(2-allylphenyl)ethan-1-one (64664-07-9)

Guidance literature:

1-bromo-2-(1,1-dimethoxyethyl)benzene; With magnesium; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Inert atmosphere;

allyl bromide; In tetrahydrofuran; at 0 - 80 ℃; for 2h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; for 1h; Inert atmosphere;

DOI:10.1039/c6cc01915c

Reference yield: 89.0%

2-bromophenyl methyl ketone (2142-69-0) + allyltributylstanane (24850-33-7) → 1-(2-allylphenyl)ethan-1-one (64664-07-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride; In tetrahydrofuran; for 12h; Inert atmosphere; Reflux;

DOI:10.1021/ja404342j

Reference yield: 86.0%

allyl methyl carbonate (35466-83-2) + 4-methoxy-N-(1-phenylethylidene)aniline (2743-00-2) → 1-(2-allylphenyl)ethan-1-one (64664-07-9)

Guidance literature:

With dimanganese decacarbonyl; sodium acetate; In 1,4-dioxane; at 100 ℃; for 14h; Schlenk technique; Inert atmosphere;

DOI:10.1002/anie.201601560

upstream raw materials:

Allyl acetate

1-(2-chlorophenyl)ethanone

2-bromophenyl methyl ketone

allyltributylstanane

Downstream raw materials:

1,3-dimethylisoquinoline

(H₂CCHCH₂C₆H₄COCH₃)Ni((C₆H₁₁)3P)

1-(2-propylphenyl)ethan-1-one

Refernces

• 1、 Ali, Shaukat,Huo, Jiaqi,Wang, Congyang. "Manganese-Catalyzed Aromatic C-H Allylation of Ketones". supporting information. p. 6961 - 6965. Retrieved 2019/09/30.
• 2、 Kawai, Kentaro,Bunno, Youka,Yoshino, Tatsuhiko,Matsunaga, Shigeki. "Weinreb Amide Directed Versatile C?H Bond Functionalization under (η5-Pentamethylcyclopentadienyl)cobalt(III) Catalysis". . p. 10231 - 10237. Retrieved 2018/07/29.