6-(4-Methylpiperazin-1-yl)pyridin-3-amine

Base Information

Chemical Name:6-(4-Methylpiperazin-1-yl)pyridin-3-amine
CAS No.:55403-35-5
Molecular Formula:C10H16N4
Molecular Weight:192.264
Hs Code.:2933990090
European Community (EC) Number:819-101-3
DSSTox Substance ID:DTXSID80376932
Nikkaji Number:J3.018.774A
Wikidata:Q82165877
Mol file:55403-35-5.mol

Synonyms:6-(4-methylpiperazin-1-yl)pyridin-3-amine;55403-35-5;3-Amino-6-(4-methylpiperazin-1-yl)pyridine;6-(4-methylpiperazino)-3-pyridinamine;6-(4-methyl-piperazin-1-yl)-pyridin-3-ylamine;MFCD03425719;6-(4-methyl-1-piperazinyl)-3-pyridinamine;3-Amino-6-(4-methyl-1-piperazinyl)pyridine;SCHEMBL55623;3-PYRIDINAMINE, 6-(4-METHYL-1-PIPERAZINYL)-;DTXSID80376932;NZTCEWZBMOTKCJ-UHFFFAOYSA-N;STK352640;AKOS000264471;AB14685;6-(4-Methylpiperazino)pyridine-3-amine;SY127917;6-(4-methylpiperazin-l-yl)pyridin-3-amine;1-(5-Aminopyridin-2-yl)-4-methylpiperazine;6-(4-methylpiperazin-1-yl)pyridine-3-amine;CS-0036514;FT-0680023;6-(4-methylpiperazine-1-yl)pyridine-3-amine;EN300-26161;6-(4-Methyl-piperazin-1-yl)pyridin-3-ylamine;6-(4-methylpiperazin-1-yl)-pyridin-3-ylamine;11R-0615;J-518032;6-(4-methylpiperazin-1-yl)pyridin-3-amine, AldrichCPR;Z220630974

Suppliers and Price of 6-(4-Methylpiperazin-1-yl)pyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(4-Methyl-1-piperazinyl)-3-pyridinamine
500mg
$ 200.00

SynQuest Laboratories
5-Amino-2-(4-methylpiperazin-1-yl)pyridine
1 g
$ 304.00

Matrix Scientific
6-(4-Methylpiperazino)-3-pyridinamine >95%
1g
$ 340.00

Matrix Scientific
6-(4-Methylpiperazino)-3-pyridinamine >95%
5g
$ 1040.00

J&W Pharmlab
6-(4-Methyl-piperazin-1-yl)-pyridin-3-ylamine 96%
25g
$ 1080.00

Crysdot
6-(4-Methylpiperazin-1-yl)pyridin-3-amine 95+%
5g
$ 452.00

Chemenu
6-(4-Methylpiperazino)-3-pyridinamine 95%
5g
$ 427.00

ChemBridge Corporation
6-(4-methyl-1-piperazinyl)-3-pyridinamine 95%
250 mg
$ 64.00

Atlantic Research Chemicals
6-(4-Methylpiperazin-1-yl)pyridin-3-amine 95%
1gm:
$ 166.12

American Custom Chemicals Corporation
6-(4-METHYLPIPERAZINO)-3-PYRIDINAMINE 95.00%
1G
$ 379.05

Total 32 raw suppliers

Chemical Property of 6-(4-Methylpiperazin-1-yl)pyridin-3-amine

Chemical Property:

Vapor Pressure:3E-06mmHg at 25°C
Melting Point:106-108 °C
Refractive Index:1.593
Boiling Point:388.7 °C at 760 mmHg
PKA:9.35±0.29(Predicted)
Flash Point:188.9 °C
PSA：45.39000
Density:1.142 g/cm³
LogP:0.99970
Storage Temp.:Keep in dark place,Sealed in dry,Store in freezer, under -20°C
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:192.137496527
Heavy Atom Count:14
Complexity:177

Purity/Quality:

99%, ^*data from raw suppliers

6-(4-Methyl-1-piperazinyl)-3-pyridinamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C2=NC=C(C=C2)N

Technology Process of 6-(4-Methylpiperazin-1-yl)pyridin-3-amine

There total 8 articles about 6-(4-Methylpiperazin-1-yl)pyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 55403-34-4
1-methyl-4-(5-nitropyridin-2-yl)piperazine

: 55403-35-5
6-(4-methyl-1-piperazinyl)-3-pyridinylamine

Guidance literature:: With 10% Pd/C; hydrogen; In methanol; for 3h; under 1810.07 - 2068.65 Torr;
DOI:10.1021/jm800072z

Reference yield: 100.0%

: 55403-35-5
6-(4-methyl-1-piperazinyl)-3-pyridinylamine

Guidance literature:

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 55403-35-5
6-(4-methyl-1-piperazinyl)-3-pyridinylamine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / Heating

2: hydrogen / Pd/C / methanol / 45 °C / 760 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2005.11.047