11alpha,13-Dihydroxydehydrocostuslactone

Base Information

Chemical Name:11alpha,13-Dihydroxydehydrocostuslactone
CAS No.:96552-47-5
Molecular Formula:C₁₅H₂₀O₄
Molecular Weight:264.321
Hs Code.:
DSSTox Substance ID:DTXSID001110038
Nikkaji Number:J916.518E
Wikidata:Q105243441
ChEMBL ID:CHEMBL2270294

Synonyms:CHEMBL2270294;DTXSID001110038;11alpha,13-Dihydroxydehydrocostuslactone;(3R,3aR,6aR,9aR,9bR)-Decahydro-3-hydroxy-3-(hydroxymethyl)-6,9-bis(methylene)azuleno[4,5-b]furan-2(3H)-one;96552-47-5

Suppliers and Price of 11alpha,13-Dihydroxydehydrocostuslactone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 11alpha,13-Dihydroxydehydrocostuslactone

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:264.13615911
Heavy Atom Count:19
Complexity:455

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=C1CCC2C(C3C1CCC3=C)OC(=O)C2(CO)O
Isomeric SMILES:C=C1CC[C@@H]2[C@@H]([C@@H]3[C@H]1CCC3=C)OC(=O)[C@@]2(CO)O

Technology Process of 11alpha,13-Dihydroxydehydrocostuslactone

There total 1 articles about 11alpha,13-Dihydroxydehydrocostuslactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 74299-48-2,93219-83-1,477-43-0
dehydrocostus lactone

: 96552-47-5
(11R)-11,13-dihydroxy-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide

: 272781-01-8
(3R,3aS,6aR,9aR,9bS)-3-{[oxy]methyl}-6,9-dimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one

: (11S)-13-hydroxy-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium carbonate; at 90 - 95 ℃; for 168h;
DOI:10.1021/jf0005364

Reference yield: 57.0%

: 98-59-9
p-toluenesulfonyl chloride

: 96552-47-5
(11R)-11,13-dihydroxy-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide

: 1094604-04-2
(11S)-11-chloro-13-(p-toluenesulfonyloxy)-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide

: 1094604-03-1
(11R)-11-hydroxy-13-(p-toluenesulfonyloxy)-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide

: (3R,11R)-3,13-dihydroxy-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide

Guidance literature:: With pyridine; at 20 ℃; for 72h;
DOI:10.1016/j.tet.2008.09.024

Reference yield: 10.0%

: 96552-47-5
(11R)-11,13-dihydroxy-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide

: 94-36-0
dibenzoyl peroxide

: (6R,7S,11R)-11-hydroxy-13-benzoyloxy-4⁽¹⁵⁾,10⁽¹⁴⁾-diene-guaian-6,12-olide

: (6R,7S,11R)-11,13-dibenzoyloxy-4⁽¹⁵⁾,10⁽¹⁴⁾-diene-guaian-6,12-olide

Guidance literature:: (11R)-11,13-dihydroxy-guaiane-4⁽¹⁵⁾,10⁽¹⁴⁾-dien-6,12-olide; With potassium hydride; In tetrahydrofuran; at 0 ℃; Inert atmosphere;

dibenzoyl peroxide; With 2-bromo-4-methyl-2H-furan-5-one; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/jf900870j