1-PYRROLIDINECARBOXYLIC ACID, 2-(2-OXOETHYL)-, 1,1-DIMETHYLETHYL ESTER

Base Information

• Chemical Name: 1-PYRROLIDINECARBOXYLIC ACID, 2-(2-OXOETHYL)-, 1,1-DIMETHYLETHYL ESTER
• CAS No.: 170491-62-0
• Molecular Formula: C₁₁H₁₉NO₃
• Molecular Weight: 213.277
• Hs Code.: 2933990090
• Mol file: 170491-62-0.mol

Synonyms:2-(2-oxoethyl)pyrrolidine-1-carboxylic acid tert-butyl ester;1,1-dimethylethyl 2-(2-oxoethyl)pyrrolidine-1-carboxylate;TERT-BUTYL 2-(FORMYLMETHYL)PYRROLIDINE-1-CARBOXYLATE;1-N-BOC-2-(FORMYLMETHYL)PYRROLIDINE;

Chemical Property of 1-PYRROLIDINECARBOXYLIC ACID, 2-(2-OXOETHYL)-, 1,1-DIMETHYLETHYL ESTER

Chemical Property:

• PSA: 46.61000
• LogP: 1.91280
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl2-(2-oxoethyl)pyrrolidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-PYRROLIDINECARBOXYLIC ACID, 2-(2-OXOETHYL)-, 1,1-DIMETHYLETHYL ESTER

There total 8 articles about 1-PYRROLIDINECARBOXYLIC ACID, 2-(2-OXOETHYL)-, 1,1-DIMETHYLETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(2-hydroxyethyl)pyrrolidine-1-carboxylic acid tert-butyl ester (220312-34-5) → 2-(2-oxoethyl)pyrrolidine-1-carboxylic acid tert-butyl ester (170491-62-0)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 4h;

Reference yield: 100.0%

2-(R)-Vinyl-pyrrolidine-1-carboxylic Acid Tert-Butyl Ester (176324-60-0) → 2-(2-oxoethyl)pyrrolidine-1-carboxylic acid tert-butyl ester (170491-62-0)

Guidance literature:

2-(R)-Vinyl-pyrrolidine-1-carboxylic Acid Tert-Butyl Ester; With sodium hydroxide; dihydrogen peroxide; bis-(1,2-dimethylpropyl)borane; In tetrahydrofuran;

With oxalyl dichloride; triethylamine; In dichloromethane; dimethyl sulfoxide;

DOI:10.3987/COM-98-S(H)13

Reference yield: 48.0%

tert-butyl 2-methoxypyrrolidine-1-carboxylate (144688-69-7) + ethyl vinyl ether (109-92-2,25104-37-4) → 2-(2-oxoethyl)pyrrolidine-1-carboxylic acid tert-butyl ester (170491-62-0)

Guidance literature:

With hydrogenchloride; sodium dodecyl-sulfate; In water; at 20 ℃;

DOI:10.1016/j.tetlet.2004.02.009

upstream raw materials:

2-(R)-Vinyl-pyrrolidine-1-carboxylic Acid Tert-Butyl Ester

tert-butyl 2-methoxypyrrolidine-1-carboxylate

ethyl vinyl ether

tert-butyl 2-(2-(methoxy(methyl)amino)-2-oxoethyl)pyrrolidine-1-carboxylate

Downstream raw materials:

1,1-diethyl-2-[2-((indan-2-yl)(phenyl)amino)ethyl]pyrrolidinium iodide

2-[2-(((indan-2-yl)phenyl)amino)ethyl]pyrrolidine-1-carboxylic acid tert-butyl ester

2-[2-(((indan-2-yl)phenyl)amino)ethyl]pyrrolidine