Technology Process of 1,4-Bis<4-(5-formyl-2,4-dimethylpyrrol-3-yl)butyl>benzene
There total 14 articles about 1,4-Bis<4-(5-formyl-2,4-dimethylpyrrol-3-yl)butyl>benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 9 steps
1: ethanol
2: aq. KOH
3: SOCl2 / 0.5 h / Heating
4: 57 percent / SnCl4 / CH2Cl2; nitromethane / Ambient temperature
5: 80 percent / B2H6 / tetrahydrofuran
6: 86 percent / PhCH2ONa / Heating
7: H2 / 10percent Pd/C / tetrahydrofuran / 760 Torr
8: dimethylformamide / 2 h / Heating
9: POCl3 / CH2Cl2 / 0.5 h
With
potassium hydroxide; thionyl chloride; hydrogen; tin(IV) chloride; sodium phenyl-methanolate; diborane; trichlorophosphate;
palladium on activated charcoal;
In
tetrahydrofuran; nitromethane; ethanol; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 10 steps
1: HBr
2: ethanol
3: aq. KOH
4: SOCl2 / 0.5 h / Heating
5: 57 percent / SnCl4 / CH2Cl2; nitromethane / Ambient temperature
6: 80 percent / B2H6 / tetrahydrofuran
7: 86 percent / PhCH2ONa / Heating
8: H2 / 10percent Pd/C / tetrahydrofuran / 760 Torr
9: dimethylformamide / 2 h / Heating
10: POCl3 / CH2Cl2 / 0.5 h
With
potassium hydroxide; thionyl chloride; hydrogen bromide; hydrogen; tin(IV) chloride; sodium phenyl-methanolate; diborane; trichlorophosphate;
palladium on activated charcoal;
In
tetrahydrofuran; nitromethane; ethanol; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 12 steps
1: 1) SOCl2, 2) NEt3
2: B2H6
3: HBr
4: ethanol
5: aq. KOH
6: SOCl2 / 0.5 h / Heating
7: 57 percent / SnCl4 / CH2Cl2; nitromethane / Ambient temperature
8: 80 percent / B2H6 / tetrahydrofuran
9: 86 percent / PhCH2ONa / Heating
10: H2 / 10percent Pd/C / tetrahydrofuran / 760 Torr
11: dimethylformamide / 2 h / Heating
12: POCl3 / CH2Cl2 / 0.5 h
With
potassium hydroxide; thionyl chloride; hydrogen bromide; hydrogen; tin(IV) chloride; triethylamine; sodium phenyl-methanolate; diborane; trichlorophosphate;
palladium on activated charcoal;
In
tetrahydrofuran; nitromethane; ethanol; dichloromethane; N,N-dimethyl-formamide;