19417-58-4

Basic information

• Product Name: 3,3'-(1,4-phenylene)dipropan-1-ol
• Synonyms: 3,3'-(1,4-phenylene)dipropan-1-ol;1,4-Benzenedipropanol
• CAS NO: 19417-58-4
• Molecular Formula: C₁₂H₁₈O₂
• Molecular Weight: 194.27012
• Mol File: 19417-58-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,3'-(1,4-phenylene)dipropan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-(1,4-phenylene)dipropan-1-ol(19417-58-4)
• EPA Substance Registry System: 3,3'-(1,4-phenylene)dipropan-1-ol(19417-58-4)

Safety Data

• Hazardous Substances Data: 19417-58-4(Hazardous Substances Data)

Upstream product

• 2664-28-0 1,4-diallylbenzene 
• 70364-29-3 3-[4-(2-ethoxycarbonyl-ethyl)-phenyl]-propionic acid ethyl ester 
• 7549-44-2 dimethyl-1,4-phenylenediacrylate 
• 35288-49-4 p-phenylenediacrylic diacid dichloride 
• 623-27-8 terephthalaldehyde, 
• 16323-43-6 1,4-phenylenediacrylic acid 
• 4251-21-2 3,3'-(1,4-phenylene)dipropanoic acid 
• 23746-57-8 diethyl (2E,2′E)-3,3′-benzene-1,4-diylbis-prop-2-enoate 
• 5312-03-8 dimethyl 3,3'-(1,4-phenylene)dipropanoate 

Downstream Products

• 1239517-47-5 3,3'-(1,4-phenylene)bis(propane-3,1-diyl)bis(4-methylbenzenesulfonate) 
• 1048954-44-4 3-(4-(3-(triisopropylsilyloxy)propyl)phenyl)propan-1-ol 
• 154674-78-9 1,4-Bis<3-(trifluormethylsulfonyloxy)propyl>benzol 
• 137334-86-2 1,4-bis(6-diazo-4,4-dimethyl-5-oxohexyl)benzene 
• 137334-87-3 1,4-bis<4,4-dimethyl-5-(ethoxycarbonyl)pentyl>benzene 
• 137334-84-0 1,4-bis(4-carboxy-4-methylpentyl)benzene 
• 137334-85-1 1,4-bis<4-(chloroformyl)-4-methylpentyl>benzene 
• 144582-39-8 C₆₀H₇₅N₇O₉ 
• 144582-38-7 C₅₈H₇₁N₇O₉ 
• 144582-37-6 C₅₈H₇₂N₆O₈ 
• 144582-06-9 1,4-Bis<4-<2-((5-ethoxycarbonyl-3-ethyl-4-methylpyrrol-2-yl)methyl)-5-(2-cyano-2-methoxycarbonylvinyl)-4-methylpyrrol-3-yl>butyl>benzene 
• 144582-42-3 C₄₈H₆₁N₅O₇ 
• 144582-41-2 C₄₆H₅₇N₅O₇ 
• 144582-40-1 C₄₆H₅₈N₄O₆ 

Relevant articles and documents

Selective Formation of Inter- and Intramolecular A-D-A π-π Stacking: Solid-State Structures of Bis(pyridiniopropyl)benzenes

The synthesis and molecular structures of bis(pyridiniopropyl)benzene derivatives, [1,4-(4-R-C5H4N+CH 2CH2CH2)2-C6H 4][X-2 (1, R = H, X = I; 2, R = tBu, X = Br) have been investigated. Compound 1 adopts a linear structure in the solid state and the crystal packing geometry can be defined as isolated triplets formed by the phenylene ring of one molecule and two pyridinium rings of two neighboring molecules. In contrast, compound 2 has an S-shaped arrangement, and an intramolecular acceptor-donor-acceptor triplet is formed among the central phenylene ring and two terminal pyridinium rings in the same molecule. Such a distinct difference in the crystal structures of 1 and 2 can be ascribed to the substituent on the pyridinium unit. The steric repulsion of the bulky tert-butyl group hinders intermolecular A-D-A π-π stacking. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

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(Chemical Equation Presented) Rhodium- and copper-catalyzed methylenation reactions with trimethylsilyldiazomethane, triphenylphosphine, and 2-propanol were used to react chemoselectively with aldehydes, alkoxymethylketones, and triftuoromethylketones in substrates also containing a less reactive carbonyl group. Terminal alkenes were obtained in high yields, and no protecting group was necessary in the methylenation process.

Linked cyclic polyamines with activity against hiv.

There is disclosed a pharmaceutical composition comprising as active ingredient a linked cyclic compound of general formula I,Z - R - A - R' - Y in which Z and Y are independently cyclic polyamine moieties having from 9 to 32 ring members and from 3 to 8 amine nitrogens in the ring spaced by 2 or more carbon atoms from each other, ???A is an aromatic or heteroaromatic moiety, ???R and R' are each a substituted or unsubstituted alkylene chain or heteroatom containing chain. or an acid addition salt or metal complex thereof, in admixture or association with a pharmaceutically acceptable diluent or carrier.

Synthesis and characterization of derivatized capped porhyrins

The syntheses of porphyrins carrying either a fully hydrophobic cavity with a benzene moiety (32a,b) or a polar cavity with an amidobenzene (32c-d) are described.Terephthaldehyde (1) was converted to benzene-bisalkanoic acids (8, 10) and nitrobenzene-bisalkanoic acids (13 and 16) by using standard methods.The corresponding diacid chlorides 17a-d were used to acylate two equivalents of a β-unsubstituted pyrrole, and the ketonic groups were reduced by diborane.Following the transformation of the nitro function to the acetamide, appropriate modifications of the ethyl ester functions afforded the key bisformylpyrroles 25a-d.The cyanoacrylate-protected formyl pyrrole derivatives were monochlorinated at the α-methyl groups and condensed with two equivalents of an α-unsubstituted pyrrole to give the dipyrromethane dimers.Strong aqueous alkali caused saponification of the two ester groups and deprotection of the formyl functions to produce the dipyrromethane dimer 30, which, after thermal decarboxylation, was cyclized intramolecularly in acidic medium to give the porphyrins 32 (n = 4 or 5, X = H or NHCOCH3).

Synthesis and Properties of 4,4,9,9-Tetramethylparacyclophane-5,6,7,8-tetrone

The synthesis of 4,4,9,9-tetramethylparacyclophane-5,6,7,8-tetrone (26) has been achieved in a multistep procedure.Compound 26 is the first cyclic tetraketone whose structure has been studied by X-ray analysis.The key intermediates were 4,4,9,9-tetramethylparacyclophane-6,7-dione (22), 6,7-bis-4,4,9,9-tetramethylparacyclophane-5,7-diene (24), and two epimeric 5,8-dihydroxy-4,4,9,9-tetramethylparacyclophane-6,7-diones 25a and 25b.X-ray analyses have been performed on 24, 25b and 26.That on 24 reveals a dihedral angle of 57 deg between the two silyenol ether groups.The product analyses and the configurations of 25a and 25b together with the isolation of the bis(epoxide) intermediate 28 allow conclusions to be drawn on the oxidation mechanism of 24 with m-CPBA (Rubottom reaction).The stability of 26 is ascribed to steric factors.