CYCLOHEXANECARBOXYLIC ACID, 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-, (1R,3S)-

Base Information

Chemical Name:CYCLOHEXANECARBOXYLIC ACID, 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-, (1R,3S)-
CAS No.:222530-39-4
Molecular Formula:C12H21 N O4
Molecular Weight:243.303
Hs Code.:2922498590
Mol file:222530-39-4.mol

Synonyms:(1R,3S)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid;(1R,3S)-3-[(tert-butoxycarbonyl)amino]cyclohexane carboxylic acid;(1R,3S)-3-(tert-butoxycarbonylamino)aminocyclohexanecarboxylic acid;Boc-L-γ-Ach-OH;(1R,3S)-3-(tert-butoxycarbonylamino)cyclohexane-carboxylic acid;(1R,3S)-3-[(tert-butyloxycarbonyl)amino]cyclohexanecarboxylic acid;(1R,3S)-3-[(tert-butoxycarbonyl)amino]cyclohexanecarboxylic acid;

Suppliers and Price of CYCLOHEXANECARBOXYLIC ACID, 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-, (1R,3S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1R,3S)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid
10mg
$ 45.00

TCI Chemical
(1R,3S)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid >97.0%(GC)(T)
1g
$ 755.00

SynQuest Laboratories
(1R,3S)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic acid 97.0%
1 g
$ 975.00

J&W Pharmlab
(1R,3S)-3-Boc-amino-cyclohexanecarboxylicacid 97%
5g
$ 1590.00

J&W Pharmlab
(1R,3S)-3-Boc-amino-cyclohexanecarboxylicacid 97%
250mg
$ 175.00

J&W Pharmlab
(1R,3S)-3-Boc-amino-cyclohexanecarboxylicacid 97%
100mg
$ 137.00

J&W Pharmlab
(1R,3S)-3-Boc-amino-cyclohexanecarboxylicacid 97%
50mg
$ 115.00

J&W Pharmlab
(1R,3S)-3-Boc-amino-cyclohexanecarboxylicacid 97%
1g
$ 398.00

J&W Pharmlab
(1R,3S)-3-Boc-amino-cyclohexanecarboxylicacid 97%
500mg
$ 249.00

Crysdot
(1R,3S)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid 95+%
1g
$ 495.00

Total 17 raw suppliers

Chemical Property of CYCLOHEXANECARBOXYLIC ACID, 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-, (1R,3S)-

Chemical Property:

Boiling Point:396.7±31.0 °C(Predicted)
PKA:4.62±0.10(Predicted)
PSA：75.63000
Density:1.12±0.1 g/cm3(Predicted)
LogP:2.54540
Storage Temp.:2-8°C
Solubility.:soluble in Methanol

Purity/Quality:

98% ^*data from raw suppliers

(1R,3S)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of CYCLOHEXANECARBOXYLIC ACID, 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-, (1R,3S)-

There total 13 articles about CYCLOHEXANECARBOXYLIC ACID, 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-, (1R,3S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 851075-68-8
ethyl (1R,3S)-3-[(tert-butoxycarbonyl)amino]cyclohexanecarboxylate

: 222530-39-4,218772-92-0,222530-33-8
(1R,3S)-3-(tert-butoxycarbonylamino)aminocyclohexanecarboxylic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 50 ℃; for 12h;
DOI:10.1016/j.bmc.2005.01.033

Reference yield:

: 99-05-8,159139-79-4
meta-aminobenzoic acid

: 222530-39-4,218772-92-0,222530-33-8
(1R,3S)-3-(tert-butoxycarbonylamino)aminocyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / aq. NaOH; H₂ / Raney Ni / 1 h / 150 °C / 68400 - 76000 Torr

2: aq. DIEA / dioxane / 3 h / 20 °C

With sodium hydroxide; hydrogen; N-ethyl-N,N-diisopropylamine; nickel; In 1,4-dioxane;
DOI:10.1002/chem.200500478