2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-((2-methoxyethoxy)methyl)benzenesulfonamide

Base Information

Chemical Name:2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-((2-methoxyethoxy)methyl)benzenesulfonamide
CAS No.:195447-73-5
Molecular Formula:C₁₅H₁₉BrN₂O₅S
Molecular Weight:419.296
Hs Code.:
DSSTox Substance ID:DTXSID001130109

Synonyms:195447-73-5;2-Bromo-N-(4,5-dimethyl-3-isoxazolyl)-N-[(2-methoxyethoxy)methyl]benzenesulfonamide;2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-((2-methoxyethoxy)methyl)benzenesulfonamide;Benzenesulfonamide, 2-bromo-N-(4,5-dimethyl-3-isoxazolyl)-N-[(2-methoxyethoxy)methyl]-;SCHEMBL6640127;ASFLNXOSWWWECK-UHFFFAOYSA-N;DTXSID001130109

Suppliers and Price of 2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-((2-methoxyethoxy)methyl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-((2-methoxyethoxy)methyl)benzenesulfonamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:418.01981
Heavy Atom Count:24
Complexity:487

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(ON=C1N(COCCOC)S(=O)(=O)C2=CC=CC=C2Br)C

Technology Process of 2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-((2-methoxyethoxy)methyl)benzenesulfonamide

There total 3 articles about 2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-((2-methoxyethoxy)methyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 3970-21-6
2-Methoxyethoxymethyl chloride

: 195447-72-4
N-(4,5-dimethyl-3-isoxazolyl)-2-bromobenzenesulfonamide

: 195447-73-5
2-Bromo-N-(4,5-dimethyl-3-isoxazolyl)-N-[(2-methoxyethoxy)methyl]-benzenesulfonamide

Guidance literature:: N-(4,5-dimethyl-3-isoxazolyl)-2-bromobenzenesulfonamide; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

2-Methoxyethoxymethyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 1.5h; Further stages.;
DOI:10.1021/jm020289q

Reference yield:

: 2905-25-1
o-bromobenzenesulfonyl chloride

: 195447-73-5
2-Bromo-N-(4,5-dimethyl-3-isoxazolyl)-N-[(2-methoxyethoxy)methyl]-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 84 percent / 4-(dimethylamiono)pyridine; pyridine / 6.5 h / 40 °C

2.1: NaH / dimethylformamide / 0.5 h / 20 °C

2.2: 75 percent / dimethylformamide / 1.5 h / 20 °C

With pyridine; dmap; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1021/jm020289q