tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Base Information

Chemical Name:tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate
CAS No.:448956-58-9
Molecular Formula:C₄₀H₄₆N₂O₈
Molecular Weight:682.814
Hs Code.:

Synonyms:tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Suppliers and Price of tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

There total 8 articles about tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 135054-68-1
(3R,5S)-6-<(methylsulfonyl)oxy>-3,5-O-isopropylidene-3,5-dihydroxyhexanoic acid tert-butyl ester

: 448956-61-4
4-(4-{[benzyl-(2-methyl-3-nitro-phenyl)-amino]-methyl}-phenoxy)-phenol

: 448956-58-9
tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Guidance literature:: With 18-crown-6 ether; potassium carbonate; In dimethyl sulfoxide; at 80 ℃; for 18h;
DOI:10.1016/j.bmcl.2004.06.021

Reference yield: 62.0%

: 448956-58-9
tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Guidance literature:

Reference yield:

: 100-39-0
benzyl bromide

: 448956-58-9
tert-butyl 6-O-[4-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenyl]-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / i-Pr₂NEt / dimethylformamide / 12 h / 90 °C

2: 95 percent / Pd(PPh₃)4; PhSiH₃ / CH₂Cl₂ / 1 h / 20 °C

3: 62 percent / K₂CO₃; 18-crown-6 / dimethylsulfoxide / 18 h / 80 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 18-crown-6 ether; phenylsilane; potassium carbonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.06.021