1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane

Base Information

Chemical Name:1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane
CAS No.:1089758-68-8
Molecular Formula:C₂₄H₃₀BrClN₂O₂
Molecular Weight:493.871
Hs Code.:

Synonyms:1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane

Suppliers and Price of 1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane

There total 2 articles about 1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1089210-23-0
5-bromo-2,3-dihydro-2,2-dimethyl-7-(4-bromo-butoxy)-benzofuran

: 6640-24-0
N-(m-chlorophenyl)piperazine

: 1089758-68-8
1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 16h; Heating / reflux;

Reference yield:

: 250289-97-5
5-bromo-2,2-dimethyl-2,3-dihydrobenzofuran-7-ol

: 1089758-68-8
1-[(5-bromo-2,3-dihydro-2,2-dimethyl-benzofuran-7-yl)-oxy]-4-[4-(3-chloro-phenyl)-piperazin-1-yl]-butane

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride / dichloromethane; water / 4 h / 20 - 40 °C

2: sodium hydroxide / water / 16 h / 20 °C / Heating / reflux

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; water;