N-cyclopropyl-2-phenoxyacetamide

Base Information

• Chemical Name: N-cyclopropyl-2-phenoxyacetamide
• CAS No.: 321532-64-3
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.23

Synonyms:N-cyclopropyl-2-phenoxyacetamide

Chemical Property of N-cyclopropyl-2-phenoxyacetamide

Chemical Property:

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Technology Process of N-cyclopropyl-2-phenoxyacetamide

There total 1 articles about N-cyclopropyl-2-phenoxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-N-cyclopropylacetamide (19047-31-5) + phenol (108-95-2,27073-41-2) → N-cyclopropyl-2-phenoxyacetamide (321532-64-3)

Guidance literature:

With potassium carbonate; In toluene; at 105 - 115 ℃;

DOI:10.1055/s-0032-1318389

Reference yield: 72.0%

N-cyclopropyl-2-phenoxyacetamide (321532-64-3) → D,L-cis-phenylcyclopropylamine (34535-98-3)

Guidance literature:

With potassium hydroxide; In 1-methyl-pyrrolidin-2-one; toluene; at 120 - 130 ℃;

DOI:10.1055/s-0032-1318389

upstream raw materials:

2-chloro-N-cyclopropylacetamide

phenol

Downstream raw materials:

D,L-cis-phenylcyclopropylamine

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