4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

Base Information

Chemical Name:4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester
CAS No.:909415-14-1
Molecular Formula:C₁₈H₂₄N₂O₈
Molecular Weight:396.397
Hs Code.:

Synonyms:4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

Suppliers and Price of 4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

There total 9 articles about 4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

: 909415-14-1
4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

Guidance literature:: 4-[(3'-methoxycarbonylpropyl)oxy]-3-methoxy-2-nitrobenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃;

(S)-1-Pyrrolidin-2-yl-methanol; With triethylamine; In dichloromethane; at -30 - 20 ℃;

Reference yield: 100.0%

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

: methyl 4-(4-(chlorocarbonyl)-2-methoxy-5-nitrophenoxy)butanoate

: 909415-14-1
4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

Guidance literature:: With triethylamine; In dichloromethane; at -30 - 20 ℃;
DOI:10.1021/jm051199z

Reference yield: 74.0%

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

: 349536-24-9
4-[(3'-methoxycarbonylpropyl)oxy]-3-methoxy-2-nitrobenzoic acid

: 909415-14-1
4-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]butanoic acid methyl ester

Guidance literature:: 4-[(3'-methoxycarbonylpropyl)oxy]-3-methoxy-2-nitrobenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

(S)-1-Pyrrolidin-2-yl-methanol; With triethylamine; In dichloromethane; at -30 ℃; for 3h; Reagent/catalyst; Temperature; Inert atmosphere;