4-Methyl-6-phenoxypyrimidine

Base Information

Chemical Name:4-Methyl-6-phenoxypyrimidine
CAS No.:55849-46-2
Molecular Formula:C11H10N2O
Molecular Weight:186.213
Hs Code.:2933599090
DSSTox Substance ID:DTXSID70506680
Wikidata:Q82362538
Mol file:55849-46-2.mol

Synonyms:4-METHYL-6-PHENOXYPYRIMIDINE;55849-46-2;6-Methyl-4-phenoxypyrimidine;4-methyl-6-phenoxy-pyrimidine;SCHEMBL753276;DTXSID70506680;A830839

Suppliers and Price of 4-Methyl-6-phenoxypyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Methyl-6-phenoxypyrimidine

Chemical Property:

Boiling Point:299.7 °C at 760 mmHg
PKA:2.87±0.17(Predicted)
Flash Point:109.9 °C
PSA：35.01000
Density:1.144 g/cm³
LogP:2.57730
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:186.079312947
Heavy Atom Count:14
Complexity:169

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC=N1)OC2=CC=CC=C2

Technology Process of 4-Methyl-6-phenoxypyrimidine

There total 1 articles about 4-Methyl-6-phenoxypyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 3435-25-4
4-methyl-6-chloropyrimidine

: 108-95-2,27073-41-2
phenol

: 55849-46-2
4-methyl-6-phenoxypyrimidine

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 60 ℃;
DOI:10.1016/j.bmc.2006.08.044

Reference yield: 73.0%

: 55849-46-2
4-methyl-6-phenoxypyrimidine

: 95-92-1
oxalic acid diethyl ester

: 2-hydroxy-3-(6-phenoxypyrimidin-4-yl)acrylic acid ethyl ester

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1016/j.bmc.2006.08.044

Reference yield:

: 55849-46-2
4-methyl-6-phenoxypyrimidine

: C₄H₂N₂(C₆H₅O)(CHCOHCO₂H)

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / tBuOK / tetrahydrofuran / 3 h / 20 °C

2: 84 percent / aq. LiOH / methanol / 60 °C

With lithium hydroxide; potassium tert-butylate; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmc.2006.08.044