3435-25-4Relevant articles and documents
Suzuki-Miyaura and Negishi approaches to a series of forensically relevant pyridines and pyrimidines
Blachut, Dariusz,Szawkalo, Joanna,Czarnocki, Zbigniew
experimental part, p. 3496 - 3506 (2011/12/04)
A library of 5-aryl-4-methylpyrimidines, phenyl ring-substituted derivatives of 4-benzylpyrimidines, 2,6-benzylpyridines, and 2,6-dibenzyl-4-methylpyridines were prepared. The synthesis of 5-aryl-4-methylpyrimidines was accomplished by Suzuki-Miyaura cross-coupling reaction between arylboronic acids and 5-bromo-4-methylpyrimidine. The 4-benzylpyrimidines and 2,6-benzylpyridines were synthesized by treatment of 4-bromopyrimidine and 2,6-dibromopyridine derivatives with ring-substituted benzylzinc reagents. Georg Thieme Verlag Stuttgart.
