1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-4-ol

Base Information

Chemical Name:1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-4-ol
CAS No.:832715-03-4
Molecular Formula:C11H13 F3 N2 O
Molecular Weight:246.22900
Hs Code.:2933399990
Mol file:832715-03-4.mol

Synonyms:1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-4-ol;5'-Trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-ol

Suppliers and Price of 1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-ol
250mg
$ 155.00

Crysdot
1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-4-ol 95+%
1g
$ 523.00

American Custom Chemicals Corporation
4-HYDROXY-1-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERIDINE 95.00%
250MG
$ 772.70

AK Scientific
1-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-ol
250mg
$ 259.00

Acrotein
1-(5-Trifluoromethyl-2-pyridinyl)-4-piperidinol 97%
1g
$ 412.50

Total 4 raw suppliers

Chemical Property of 1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-4-ol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:82-83
Boiling Point:357.352oC at 760 mmHg
Flash Point:169.921oC
PSA：36.36000
Density:1.328g/cm3
LogP:2.12650

Purity/Quality:

97% ^*data from raw suppliers

1-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-4-ol

There total 1 articles about 1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 5382-16-1
4-HYDROXYPIPERIDINE

: 52334-81-3
2-chloro-5-trifluoromethylpyridine

: 832715-03-4
1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ol

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In isopropyl alcohol; at 160 ℃; for 2.5h; Irradiation;

Reference yield:

: 832715-03-4
1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ol

: 88-30-2
3-trifluoromethyl-4-nitrophenol

: 4-[4-nitro-3-(trifluoromethyl)phenoxy]-1-[5-(trifluoromethyl)-pyridin-2-yl]-piperidine

Guidance literature:: With di-isopropyl azodicarboxylate; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

Reference yield:

: 866615-03-4
1-fluoro-2-(methoxymethoxy)-4-(trifluoro methyl)benzene

: 832715-03-4
1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ol

: 4-[2-methoxymethoxy-4-(trifluoromethyl)-phenoxy]-1-[5-(trifluoromethyl)-pyridin-2-yl]piperidine

Guidance literature:: 1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ol; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

1-fluoro-2-(methoxymethoxy)-4-(trifluoro methyl)benzene; In N,N-dimethyl-formamide; at 100 ℃;