1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

Base Information

Chemical Name:1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide
CAS No.:808752-13-8
Molecular Formula:C₂₆H₃₆N₂O₅S
Molecular Weight:488.648
Hs Code.:

Synonyms:1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

Suppliers and Price of 1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

There total 6 articles about 1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 808752-12-7
C₂₆H₃₈N₂O₅S

: 808752-13-8
1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; for 1.41667h; cooling;
DOI:10.1016/j.bmc.2004.08.044

Reference yield:

: 60-12-8
2-phenylethanol

: 808752-13-8
1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 3 h / 20 °C

2: 93 percent / LiBH₄ / tetrahydrofuran; ethanol / 28 h / 20 °C

3: 83 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / 1.42 h / cooling

With lithium borohydride; oxalyl dichloride; dimethyl sulfoxide; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane; 3: Swern oxidation;
DOI:10.1016/j.bmc.2004.08.044

Reference yield:

: 6322-53-8,5845-53-4,7517-19-3
leucine methyl ester hydrochloride

: 808752-13-8
1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

Guidance literature:: Multi-step reaction with 5 steps

1: 66 percent / acetic acid; sodium (triacetoxy)borohydride / 1,2-dichloro-ethane / 3.5 h / 20 °C

2: 66 percent / triethylamine / CH₂Cl₂ / 2.5 h / cooling

3: 88 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 3 h / 20 °C

4: 93 percent / LiBH₄ / tetrahydrofuran; ethanol / 28 h / 20 °C

5: 83 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / 1.42 h / cooling

With lithium borohydride; oxalyl dichloride; sodium tris(acetoxy)borohydride; acetic acid; dimethyl sulfoxide; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane; 1,2-dichloro-ethane; 5: Swern oxidation;
DOI:10.1016/j.bmc.2004.08.044