2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

Base Information

Chemical Name:2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide
CAS No.:808752-15-0
Molecular Formula:C₂₁H₂₆N₂O₂S
Molecular Weight:370.516
Hs Code.:

Synonyms:2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

Suppliers and Price of 2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

There total 10 articles about 2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 808752-18-3
C₂₁H₃₀N₂O₃S

: 808752-15-0
2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; for 1.36667h; cooling;
DOI:10.1016/j.bmc.2004.08.044

Reference yield:

: 808752-13-8
1-benzyl-1-[(1-formyl-3-methylbutyl)]-3-phenethyl-3-(carbamic acid tert-butyl ester)sulfamide

: 808752-15-0
2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

Guidance literature:: With aluminium trichloride; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1016/j.bmc.2004.08.044

Reference yield:

: 66399-70-0
methyl 2-(benzylamino)-4-methylpentanoate

: 808752-15-0
2-benzyl-3-isobutyl-5-phenethyl-2,5-dihydro[1,2,5]thiadiazole-1,1-dioxide

Guidance literature:: Multi-step reaction with 5 steps

1: 66 percent / triethylamine / CH₂Cl₂ / 2.5 h / cooling

2: 88 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 3 h / 20 °C

3: 97 percent / trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

4: 89 percent / lithium borohydride / tetrahydrofuran; ethanol / 28 h / 20 °C

5: 100 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / 1.37 h / cooling

With lithium borohydride; oxalyl dichloride; dimethyl sulfoxide; triethylamine; triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane; 5: Swern oxidation;
DOI:10.1016/j.bmc.2004.08.044