N₁-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide

Base Information

• Chemical Name: N₁-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide
• CAS No.: 253877-87-1
• Molecular Formula: C₇₉H₁₀₀N₄O₁₀S₄
• Molecular Weight: 1393.95
• Mol file: 253877-87-1.mol

Synonyms:N₁-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide

Chemical Property of N₁-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide

There total 3 articles about N₁-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

bis(4-bromomethylphenyl)methane (16980-01-1) + N1-{6-[(mesitylsulfonyl)amino]hexyl}-N1-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide (253877-86-0) → N1-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N1-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide (253877-87-1)

Guidance literature:

N₁-{6-[(mesitylsulfonyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

bis(4-bromomethylphenyl)methane; In N,N-dimethyl-formamide; at 85 ℃; for 20h;

DOI:10.1021/jm991110n

Reference yield:

2-mesitylenesulphonyl chloride (773-64-8) → N1-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N1-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide (253877-87-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 95 percent / aq. NaOH / CH₂Cl₂ / 24 h / 0 - 20 °C

2.1: NaH / dimethylformamide / 1 h / 20 °C

2.2: 70 percent / dimethylformamide / 20 h / 85 °C

With sodium hydroxide; sodium hydride; In dichloromethane; N,N-dimethyl-formamide; 1.1: Sulfonylation / 2.1: Metallation / 2.2: Alkylation;

DOI:10.1021/jm991110n

Reference yield:

N1-(2-methoxy-benzyl)-hexane-1,6-diamine; compound with GENERIC INORGANIC NEUTRAL COMPONENT → N1-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N1-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide (253877-87-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 95 percent / aq. NaOH / CH₂Cl₂ / 24 h / 0 - 20 °C

2.1: NaH / dimethylformamide / 1 h / 20 °C

2.2: 70 percent / dimethylformamide / 20 h / 85 °C

With sodium hydroxide; sodium hydride; In dichloromethane; N,N-dimethyl-formamide; 1.1: Sulfonylation / 2.1: Metallation / 2.2: Alkylation;

DOI:10.1021/jm991110n

upstream raw materials:

bis(4-bromomethylphenyl)methane

N₁-{6-[(mesitylsulfonyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide

2-mesitylenesulphonyl chloride