(E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

Base Information

Chemical Name:(E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon
CAS No.:1445973-90-9
Molecular Formula:C₂₄H₁₇Cl₂NO₃S
Molecular Weight:470.376
Hs Code.:

Synonyms:(E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

Suppliers and Price of (E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of (E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

There total 3 articles about (E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1445973-83-0
C₃₅H₂₈NO₃PS

: 874-42-0
2,4-dichlorobenzaldeyhde

: 1445973-90-9
(E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

Guidance literature:: In 1,2-dichloro-ethane; for 12h; Reflux; Inert atmosphere;
DOI:10.1021/ol4015738

Reference yield:

: 113685-33-9
3-acetyl-2-methyl-1-(phenylsulfonyl)indole

: 1445973-90-9
(E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 3 h / Reflux; Inert atmosphere

2.1: tetrahydrofuran / 2 h / Reflux; Inert atmosphere

2.2: 12 h / 20 °C / Inert atmosphere

3.1: 1,2-dichloro-ethane / 12 h / Reflux; Inert atmosphere

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrahydrofuran; tetrachloromethane; 1,2-dichloro-ethane;
DOI:10.1021/ol4015738

Reference yield:

: 143774-55-4
1-(2-(bromomethyl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanone

: 1445973-90-9
(E)-1-(2-(2,4-dichlorostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl)ethanon

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 2 h / Reflux; Inert atmosphere

1.2: 12 h / 20 °C / Inert atmosphere

2.1: 1,2-dichloro-ethane / 12 h / Reflux; Inert atmosphere

In tetrahydrofuran; 1,2-dichloro-ethane;
DOI:10.1021/ol4015738