Ethyl 4-hydroxynicotinate

Base Information

Chemical Name:Ethyl 4-hydroxynicotinate
CAS No.:57905-31-4
Molecular Formula:C8H9NO3
Molecular Weight:167.162
Hs Code.:2933399990
DSSTox Substance ID:DTXSID60355785
Nikkaji Number:J907.772C
Wikidata:Q82134824
Mol file:57905-31-4.mol

Synonyms:ethyl 4-hydroxynicotinate;57905-31-4;Ethyl 4-oxo-1,4-dihydropyridine-3-carboxylate;10177-34-1;4-Hydroxy-nicotinic acid ethyl ester;ethyl 4-oxo-1H-pyridine-3-carboxylate;4-Oxo-1,4-dihydro-pyridine-3-carboxylicacidethylester;6,3-dimethoxyflavone;ETHYL4-HYDROXYNICOTINATE;SCHEMBL6640350;SCHEMBL10314672;DTXSID60355785;MFCD00234426;AKOS005199212;AKOS006332742;MB01033;AS-70528;CS-0089684;CS-0166863;FT-0618651;FT-0721291;D83257;4-oxo-1H-pyridine-3-carboxylic acid ethyl ester;ethyl 4-oxidanylidene-1H-pyridine-3-carboxylate;A831862;A869563;AC-907/25004796

Suppliers and Price of Ethyl 4-hydroxynicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl4-Hydroxynicotinate
500mg
$ 305.00

Crysdot
Ethyl4-hydroxynicotinate 95+%
10g
$ 559.00

Crysdot
Ethyl4-hydroxynicotinate 95+%
25g
$ 937.00

Crysdot
Ethyl4-hydroxynicotinate 95+%
5g
$ 372.00

Chemenu
Ethyl4-hydroxynicotinate 95%
5g
$ 352.00

Chemenu
Ethyl4-hydroxynicotinate 95%
25g
$ 884.00

Chemenu
Ethyl4-hydroxynicotinate 95%
10g
$ 529.00

Apolloscientific
Ethyl4-hydroxynicotinate 98%
1g
$ 501.00

Apolloscientific
Ethyl4-hydroxynicotinate 98%
250mg
$ 218.00

American Custom Chemicals Corporation
4-HYDROXY-NICOTINIC ACID ETHYL ESTER 95.00%
1G
$ 1030.84

Total 25 raw suppliers

Chemical Property of Ethyl 4-hydroxynicotinate

Chemical Property:

Vapor Pressure:0.00278mmHg at 25°C
Refractive Index:1.512
Boiling Point:285.6 °C at 760 mmHg
PKA:8.28±0.10(Predicted)
Flash Point:126.5 °C
PSA：59.42000
Density:1.214 g/cm³
LogP:0.96390
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:167.058243149
Heavy Atom Count:12
Complexity:266

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4-Hydroxynicotinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CNC=CC1=O
Uses Ethyl 4-Hydroxynicotinate is the ethyl ester derivative of 4-Hydroxynicotinic Acid (H952780); a reagent used in the synthesis and biological evaluation of novel imidazo[4,5-c]pyridinecarboxamide derivatives as PARP-1 inhibitors and antitumor agents.

Technology Process of Ethyl 4-hydroxynicotinate

There total 3 articles about Ethyl 4-hydroxynicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 626-64-2,157061-69-3
pyridin-4-ol

: 57905-31-4
4-Hydroxy-nicotinsaeure-ethylester

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / 240 °C / 36775.4 Torr

2: concentrated H₂SO₄

With sulfuric acid; potassium carbonate;