1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid

Base Information

Chemical Name:1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid
CAS No.:1355157-93-5
Molecular Formula:C₃₁H₃₃N₃O₄
Molecular Weight:511.621
Hs Code.:

Synonyms:1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid

There total 9 articles about 1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 874-89-5
4-Cyanobenzyl alcohol

: 1355157-93-5
1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: hydroxylamine / ethanol; water / 16 h / 74 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / acetonitrile / 18 h / 20 °C / Microwave irradiation

3: manganese(IV) oxide / 1,4-dioxane / 70 °C

4: sodium cyanoborohydride; acetic acid / dichloromethane; methanol / 20 °C

With manganese(IV) oxide; hydroxylamine; sodium cyanoborohydride; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; methanol; ethanol; dichloromethane; water; acetonitrile;

Reference yield:

: 1355159-89-5
4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde

: 52-52-8
1-amino-1-cyclopentanecarboxylic acid

: 1355157-93-5
1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid

Guidance literature:: With sodium cyanoborohydride; acetic acid; In methanol; dichloromethane; at 20 ℃;

Reference yield:

: 142031-67-2
methyl 4-bromo-3-(bromomethyl)benzoate

: 1355157-93-5
1-((4-(5-(2-(methoxymethyl)-2'-methylbiphenyl-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)(methyl)amino)cyclopentanecarboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: 96 h / Reflux

2.1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; water / Inert atmosphere; Reflux

3.1: sodium hydroxide / ethanol / 1 h / 60 °C

3.2: pH 2

4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / acetonitrile / 18 h / 20 °C / Microwave irradiation

5.1: manganese(IV) oxide / 1,4-dioxane / 70 °C

6.1: sodium cyanoborohydride; acetic acid / dichloromethane; methanol / 20 °C

With manganese(IV) oxide; sodium cyanoborohydride; potassium carbonate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; methanol; ethanol; dichloromethane; water; toluene; acetonitrile;