2-(IODOMETHYL)TETRAHYDROFURAN

Base Information

• Chemical Name: 2-(IODOMETHYL)TETRAHYDROFURAN
• CAS No.: 5831-70-9
• Molecular Formula: C5H9IO
• Molecular Weight: 212.03
• Mol file: 5831-70-9.mol

Synonyms:Tetrahydrofurfuryl iodide;2-(Iodomethyl)tetrahydrofuran;

Chemical Property of 2-(IODOMETHYL)TETRAHYDROFURAN

Chemical Property:

• Vapor Pressure: 0.309mmHg at 25°C
• Refractive Index: 1.543
• Boiling Point: 208.4 °C at 760 mmHg
• Flash Point: 79.8 °C
• PSA: 9.23000
• Density: 1.772 g/cm³
• LogP: 1.60040

Purity/Quality:

99% ^*data from raw suppliers

2-(IODOMETHYL)TETRAHYDROFURAN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(IODOMETHYL)TETRAHYDROFURAN

There total 3 articles about 2-(IODOMETHYL)TETRAHYDROFURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-Tetradecanol (112-72-1) + 1-methoxy-4-((pent-4-en-1-yloxy)methyl)benzene (180259-48-7) → 2-(iodomethyl)tetrahydrofuran (5831-70-9) + 1-Methoxy-4-tetradecyloxymethyl-benzene

Guidance literature:

With N-iodo-succinimide; In tetrahydrofuran; acetonitrile; for 3h; Ambient temperature;

DOI:10.1016/0040-4020(96)00375-4

Reference yield: 10.0%

hydroperoxyde de pentene-4 (60990-44-5,27274-31-3) → 2-(iodomethyl)tetrahydrofuran (5831-70-9) + n-Pent-4-enyl alcohol (821-09-0) + 4-pentenal (2100-17-6)

Guidance literature:

With sulfuric acid; ferrous iodide; In water; for 2h;

Reference yield:

hydroperoxyde de pentene-4 (60990-44-5,27274-31-3) → 2-(iodomethyl)tetrahydrofuran (5831-70-9) + 1,2-di(tetrahydrofuran-2-yl)ethane (1793-98-2) + n-Pent-4-enyl alcohol (821-09-0) + 4-pentenal (2100-17-6)

Guidance literature:

With acetic acid; iron(II) chloride; In water; for 2h; Product distribution; Heating; compare with other reagents;

upstream raw materials:

hydroperoxyde de pentene-4

1-Tetradecanol

1-methoxy-4-((pent-4-en-1-yloxy)methyl)benzene

Downstream raw materials:

1-methyl-4-(2-tetrahydrofuryl)-4-(phenylsulfonyl)cyclohexene

6,6-(ethylenedioxy)-3-<(2-tetrahydrofuranyl)methyl>-3-(phenylsulfonyl)cyclohexene

Tetrahydrofurfuryl alcohol

2-[3-(4-methoxyphenyl)-prop-1-yl]-tetrahydrofuran

Refernces

• 1、 Taillez, Bernard,Bertrand, Michele Paula,Surzur, Jean-Marie. "Intramolecular Addition of Alkoxy Radicals. Part 4. Reductive Cyclisation of Olefinic Hydroperoxides". . p. 547 - 554. Retrieved 2007/10/02.