2-METHYL-1,5-NAPHTHYRIDINE

Base Information

Chemical Name:2-METHYL-1,5-NAPHTHYRIDINE
CAS No.:7675-32-3
Molecular Formula:C9H8N2
Molecular Weight:144.176
Hs Code.:2933990090
Mol file:7675-32-3.mol

Synonyms:2-Methyl-1,5-diazanaphthalene;2-Methyl-1,5-naphthyridine;1,5-naphthyridine, 2-methyl-;2-methyl-1,5-naphthyridine;

Suppliers and Price of 2-METHYL-1,5-NAPHTHYRIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methyl-1,5-Naphthyridine
1g
$ 275.00

SynQuest Laboratories
2-Methyl-1,5-naphthyridine
1 g
$ 325.00

Matrix Scientific
2-Methyl-1,5-naphthyridine
5g
$ 1127.00

Crysdot
2-Methyl-1,5-naphthyridine 95+%
1g
$ 122.00

Crysdot
2-Methyl-1,5-naphthyridine 95+%
5g
$ 440.00

Apolloscientific
2-methyl-1,5-naphthyridine 95%
1g
$ 495.00

Apolloscientific
2-methyl-1,5-naphthyridine 95%
250mg
$ 225.00

Ambeed
2-Methyl-1,5-naphthyridine 95+%
5g
$ 347.00

Ambeed
2-Methyl-1,5-naphthyridine 95+%
250mg
$ 40.00

Ambeed
2-Methyl-1,5-naphthyridine 95+%
100mg
$ 26.00

Total 41 raw suppliers

Chemical Property of 2-METHYL-1,5-NAPHTHYRIDINE

Chemical Property:

Vapor Pressure:0.03mmHg at 25°C
Melting Point:62 °C
Refractive Index:1.633
Boiling Point:252.835 °C at 760 mmHg
PKA:3.29±0.10(Predicted)
Flash Point:106.326 °C
PSA：25.78000
Density:1.142 g/cm³
LogP:1.93820
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

2-Methyl-1,5-Naphthyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Methyl-1,5-Naphthyridine is a genera; reagent used in the synthesis of FIKK kinase inhibitors as anti-parasitic agents as well as 1,5-Naphthyridine Derivatives as novel TGF-β Type 1 receptor inhibitors.

Technology Process of 2-METHYL-1,5-NAPHTHYRIDINE

There total 1 articles about 2-METHYL-1,5-NAPHTHYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21203-68-9
2-methyl-5-nitropyridine

: 7675-32-3
2-methyl-[1,5]naphthyridine

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 18 h / 20 °C / 3040.2 Torr / Autoclave

2: sulfuric acid; boric acid; sodium 3-nitrobenzenesulfonate; ferrous(II) sulfate heptahydrate / water / 18 h / 135 °C

With ferrous(II) sulfate heptahydrate; sulfuric acid; palladium 10% on activated carbon; hydrogen; boric acid; sodium 3-nitrobenzenesulfonate; In methanol; water;

Reference yield: 74.3%

: 7675-32-3
2-methyl-[1,5]naphthyridine

: 1128-76-3
3-chloro-benzoic acid ethyl ester

: 764717-65-9
1-(3-chlorophenyl)-2-(1,5-naphthyridin-2-yl)ethanone

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 - 20 ℃; for 21h;
DOI:10.1021/jm0400247

Reference yield: 67.0%

: 7675-32-3
2-methyl-[1,5]naphthyridine

: 14774-77-7
p-methoxyphenyllithium

: 2-(4-methoxyphenyl)-6-methyl-1,5-naphthyridine

Guidance literature:: 2-methyl-[1,5]naphthyridine; p-methoxyphenyllithium; In tetrahydrofuran; toluene; at 0 - 25 ℃; for 12h; Inert atmosphere;

With manganese(IV) oxide; In tetrahydrofuran; toluene; at 25 ℃; for 6h;