methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine

Base Information

• Chemical Name: methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine
• CAS No.: 168848-36-0
• Molecular Formula: C₂₆H₂₇O₅P
• Molecular Weight: 450.471
• Mol file: 168848-36-0.mol

Synonyms:methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine

Chemical Property of methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine

There total 2 articles about methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 2,3-anhydro-4,6-O-benzylidene-α-D-mannopyranoside (2880-96-8,3150-15-0,3150-16-1,3257-59-8,14187-71-4,15384-57-3,19465-13-5,32976-15-1,52885-37-7,53270-02-3,53270-03-4,65391-11-9,65391-12-0,66537-92-6,67226-04-4,71184-14-0,86420-78-2,86420-79-3,91177-51-4,91177-52-5,117708-93-7,120408-72-2) + diphenylphosphane (829-85-6) → methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine (168848-36-0)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; at -35 - 20 ℃;

DOI:10.1021/ja0172013

Reference yield:

lithium diphenylphosphide (65567-06-8,4541-02-0) + methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside (3150-15-0,3150-16-1,3257-59-8,14187-71-4,15384-57-3,19465-13-5,32976-15-1,52885-37-7,53270-02-3,53270-03-4,65391-11-9,65391-12-0,66537-92-6,67226-04-4,71184-14-0,86420-78-2,86420-79-3,91177-51-4,91177-52-5,117708-93-7,120408-72-2,2880-96-8) → methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine (168848-36-0)

Guidance literature:

With ammonium chloride; Yield given. Multistep reaction; 1.) DMF, 2 h, 2.) DMF, 30 min;

DOI:10.1246/cl.1995.685

Reference yield: 92.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + methyl 3-deoxy-4,6-O-phenylmethenyl-α-D-altropyranosido-3-diphenylphosphine (168848-36-0) → methyl 4,6-O-benzylidene-3-deoxy-2-O-(diphenylphosphino)-3-(diphenylphosphinyl)-α-D-altropyranoside

Guidance literature:

With dmap; In tetrahydrofuran; dichloromethane; at 20 ℃;

DOI:10.1021/ja0172013

upstream raw materials:

lithium diphenylphosphide

methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside

methyl 2,3-anhydro-4,6-O-benzylidene-α-D-mannopyranoside

diphenylphosphane

Downstream raw materials:

C₂₇H₂₉O₅P