2,2'-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol

Base Information

• Chemical Name: 2,2'-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol
• CAS No.: 252735-70-9
• Molecular Formula: C₃₄H₅₀N₄O₄
• Molecular Weight: 578.795
• DSSTox Substance ID: DTXSID60422481
• Nikkaji Number: J1.228.986C
• Wikidata: Q82234437
• Mol file: 252735-70-9.mol

Synonyms:252735-70-9;2,2'-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol;2,2mu-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol;4-Tert-butyl-2-[2-[[5-tert-butyl-2-hydroxy-3-(morpholin-4-ylmethyl)phenyl]methylideneamino]ethyliminomethyl]-6-(morpholin-4-ylmethyl)phenol;DTXSID60422481;2,2 inverted exclamation marka-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol;2,2'-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol, 97%;2,2|I-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol

Chemical Property of 2,2'-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol

Chemical Property:

• Melting Point: 162-166?°C
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 11
• Exact Mass: 578.38320609
• Heavy Atom Count: 42
• Complexity: 787

Purity/Quality:

2,2′-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1=CC(=C(C(=C1)C=NCCN=CC2=CC(=CC(=C2O)CN3CCOCC3)C(C)(C)C)O)CN4CCOCC4

Technology Process of 2,2'-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol

There total 3 articles about 2,2'-[1,2-Ethanediylbis[(E)-(nitrilomethylidyne)]]bis[4-(tert-butyl)-6-(4-morpholinylmethyl)]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethylenediamine (107-15-3,85404-18-8) + 2-Hydroxy-3-(morpholin-4-ylmethyl)-5-tert-butylbenzaldehyde (252735-68-5) → C4NOH8CH2C6H2(OH)[C(CH3)3]CHNC2H4NCHC6H2(OH)[C(CH3)3]CH2C4NOH8 (252735-70-9)

Guidance literature:

In diethyl ether; ethanol; at 20 ℃; for 24h;

DOI:10.1039/b003436n

Reference yield:

N-(ethoxymethyl)morpholine (18811-63-7) → C4NOH8CH2C6H2(OH)[C(CH3)3]CHNC2H4NCHC6H2(OH)[C(CH3)3]CH2C4NOH8 (252735-70-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / acetonitrile / 72 h / Heating

2: 95 percent / diethyl ether; ethanol / 24 h / 20 °C

In diethyl ether; ethanol; acetonitrile; 1: Substitution / 2: Condensation;

DOI:10.1039/b003436n

Reference yield:

3-(tert-butyl)benzaldehyde (23039-28-3) → C4NOH8CH2C6H2(OH)[C(CH3)3]CHNC2H4NCHC6H2(OH)[C(CH3)3]CH2C4NOH8 (252735-70-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / acetonitrile / 72 h / Heating

2: 95 percent / diethyl ether; ethanol / 24 h / 20 °C

In diethyl ether; ethanol; acetonitrile; 1: Substitution / 2: Condensation;

DOI:10.1039/b003436n

upstream raw materials:

ethylenediamine

2-Hydroxy-3-(morpholin-4-ylmethyl)-5-tert-butylbenzaldehyde

N-(ethoxymethyl)morpholine

3-(tert-butyl)benzaldehyde