2',3',5'-tri-O-acetyl-3-[(2Z)-4-(adamantan-1-ylamino)-3-(4-methylphenyl)but-2-en-1-yl]uridine

Base Information

Chemical Name:2',3',5'-tri-O-acetyl-3-[(2Z)-4-(adamantan-1-ylamino)-3-(4-methylphenyl)but-2-en-1-yl]uridine
CAS No.:1415409-82-3
Molecular Formula:C₃₆H₄₅N₃O₉
Molecular Weight:663.768
Hs Code.:

Synonyms:2',3',5'-tri-O-acetyl-3-[(2Z)-4-(adamantan-1-ylamino)-3-(4-methylphenyl)but-2-en-1-yl]uridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2',3',5'-tri-O-acetyl-3-[(2Z)-4-(adamantan-1-ylamino)-3-(4-methylphenyl)but-2-en-1-yl]uridine

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Technology Process of 2',3',5'-tri-O-acetyl-3-[(2Z)-4-(adamantan-1-ylamino)-3-(4-methylphenyl)but-2-en-1-yl]uridine

There total 1 articles about 2',3',5'-tri-O-acetyl-3-[(2Z)-4-(adamantan-1-ylamino)-3-(4-methylphenyl)but-2-en-1-yl]uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 624-31-7
4-tolyl iodide

: 768-94-5
1-Adamantanamine

: 1415409-74-3
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(3-(buta-2,3-dienyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate

: 1415409-82-3
2',3',5'-tri-O-acetyl-3-[(2Z)-4-(adamantan-1-ylamino)-3-(4-methylphenyl)but-2-en-1-yl]uridine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane; potassium carbonate; In acetonitrile; at 80 ℃; stereoselective reaction;
DOI:10.1039/c2cc35054h