(2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide

Base Information

• Chemical Name: (2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide
• CAS No.: 73352-52-0
• Molecular Formula: C₁₇H₂₀N₂O₇
• Molecular Weight: 364.355
• Mol file: 73352-52-0.mol

Synonyms:(2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide

Chemical Property of (2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide

There total 5 articles about (2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + C13H16ClNO4 → (2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide (73352-52-0)

Guidance literature:

With pyridine; In ethyl acetate; at 25 ℃; for 1h;

DOI:10.1039/P19810002186

Reference yield:

benzyl (1R)-1-(hydroxymethyl)propylcarbamate (73395-16-1) → (2R)-N-(2-benzyloxycarbonylaminobutoxycarbonyloxy)succinimide (73352-52-0)

Guidance literature:

Reference yield:

benzyl (1R)-1-(hydroxymethyl)propylcarbamate (73395-16-1) → (2R)-N-(2-benzyloxycarbonylaminobutyloxycarbonyloxy)sucinimide (73352-52-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / CH₂Cl₂ / 3 h

2: 51 percent / pyridine / ethyl acetate / 1 h / 25 °C

With pyridine; triethylamine; In dichloromethane; ethyl acetate;

DOI:10.1039/P19810002186

upstream raw materials:

benzyl (1R)-1-(hydroxymethyl)propylcarbamate

1-hydroxy-pyrrolidine-2,5-dione

benzyl chloroformate

Downstream raw materials:

(2R)-3,6'-bis-N-benzyloxycarbonyl-1-N-(2-benzyloxycarbonylaminobutyloxycarbonyl)gentamicin B

(2R)-1-N-(2-aminobutyloxycarbonyl)gentamicin B

(2R)-1-N-(2-aminobutoxycarbonyl)-2-deoxystreptamine