cyclohexane-1,1-dicarboxylic acid monomethyl ester

Base Information

• Chemical Name: cyclohexane-1,1-dicarboxylic acid monomethyl ester
• CAS No.: 33315-64-9
• Molecular Formula: C₉H₁₄O₄
• Molecular Weight: 186.208
• Mol file: 33315-64-9.mol

Synonyms:cyclohexane-1,1-dicarboxylic acid monomethyl ester

Chemical Property of cyclohexane-1,1-dicarboxylic acid monomethyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexane-1,1-dicarboxylic acid monomethyl ester

There total 4 articles about cyclohexane-1,1-dicarboxylic acid monomethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl chloroformate (79-22-1) + Cyclohexanecarboxylic acid (98-89-5) → cyclohexane-1,1-dicarboxylic acid monomethyl ester (33315-64-9)

Guidance literature:

Cyclohexanecarboxylic acid; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at 50 - 60 ℃; for 2h;

methyl chloroformate; In tetrahydrofuran; hexane; at -75 ℃; for 0.5h;

DOI:10.3390/11050357

Reference yield: 68.0%

methyl cyclohexylcarboxylate (4630-82-4) + carbon dioxide (124-38-9,18923-20-1) → cyclohexane-1,1-dicarboxylic acid monomethyl ester (33315-64-9)

Guidance literature:

methyl cyclohexylcarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; hexane; for 0.5h;

carbon dioxide; In tetrahydrofuran; hexane; for 0.25h;

DOI:10.3390/11050357

Reference yield:

dimethyl 1,1-cyclohexanedicarboxylate (72963-31-6) → cyclohexane-1,1-dicarboxylic acid monomethyl ester (33315-64-9)

Guidance literature:

With potassium hydroxide; at 0 ℃; Hydrolysis;

upstream raw materials:

dimethyl 1,1-cyclohexanedicarboxylate

methyl cyclohexylcarboxylate

carbon dioxide

carbonic acid dimethyl ester

Downstream raw materials:

1-chlorocarbonylcyclohexane-1-carboxylic acid methyl ester